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BioWorld Science

Feb. 27, 2020

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Structural insights could enable specific activation of GPCRs

Autophagy activation may prevent metastasis

S100A12 is upregulated in papillary thyroid cancer and may serve as a diagnostic biomarker

New MRI contrast agent specifically targeting CXCR4 in liver metastases may allow early detection

Pilot study of APN-01 for the treatment of coronavirus disease COVID-19 in China

Novavax produces nanoparticle COVID-19 vaccine candidates

Prospective comparison of [68Ga]RM-2 and [68Ga]PSMA-617 PET/CT in prostate cancer

Proof-of-concept data for novel anti-CD300f ADC in preclinical models of AML

Generon presents phase II data for F-652 in acute GVHD

Positive initial data from phase IIa study of IFX-1 in Pyoderma gangraenosum

Conserved epigenetic regulators prevent healthy aging

Tonix collaborates with Southern Research on vaccine TNX-1800 for COVID-19

Sitagliptin for preventing aGvHD following myeloablative allogeneic transplantation shows promise

FDA clears start of investigator-sponsored trial of Kiadis' off-the-shelf NK cell therapy for AML

IL-6 blockade investigated in stem cell transplantation for multiple myeloma

ViiV Healthcare presents new antivirals for HIV infection

Gilead Sciences patents IRAK-4 inhibitors

Medshine Discovery discloses RET inhibitors

G1 Therapeutics identifies ER modulators

Inflazome completes first-in-human study of NLRP3 inflammasome inhibitor somalix

Genentech and Roche divulge KRAS inhibitors

MapKure initiates first-in-human study of BGB-3245 in advanced or refractory tumors

FDA approves Barhemsys for prevention and treatment of PONV

iTeos initiates phase I/II study of EOS-884448 in advanced cancers

Ascletis updates clinical trial in China with Ganovo and ritonavir for novel coronavirus pneumonia