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BioWorld Science

April 29, 2020

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Oral drug can wake up telomerase

Older siblings' example turns stem cells into heart cells

Preclinical evaluation of the survivin inhibitor FL-118 in relapsed/refractory multiple myeloma

KCNMB1 methylation increases BK channel activity, resulting in myofibroblast differentiation in IPF

Human recombinant ACE2 blocks the early stages of SARS-CoV-2 infection in cell and tissue models

First patient dosed in proof-of-concept of OTL-201 gene therapy

Phase III VOYAGER study of avapritinib does not meet primary endpoint

Tetra Bio-Pharma to develop PPP-003 for management of CRS

Topline data from phase III study of Dextenza in allergic conjunctivitis

Vicore receives regulatory approval to initiate phase II study of VP-01 in COVID-19

FDA clears IND application for CRX-100

Regenacy Pharmaceuticals discloses new HDAC1/HDAC2 inhibitors

ABBV-951 shows promising safety in patients with Parkinson's disease

Protein binder specific for hPD-1 shows strong antitumor activity in vivo

First prospective peek at Thrive's Cancerseek reveals gaps in liquid biopsy testing

Interim phase I data for ATOR-1015 presented by Alligator Bioscience

New thyroid hormone receptor beta agonists synthesized at Inventisbio Shanghai

FORMA Therapeutics describes new FAS inhibitors

New glucocorticoid receptor antagonists discovered at ORIC Pharmaceuticals

Sage Therapeutics patents GABA(A) receptor modulators

Innate's avdoralimab studied in phase II trial for patients with COVID-19 and severe pneumonia

Phase II interim results presented for GX-188E + pembrolizumab in HPV-positive cervical cancer