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BioWorld Science

May 18, 2020

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Soluble VEGFR-1 is a diagnostic marker of bladder pain syndrome/interstitial cystitis

VSY Biotechnology developing TR-C 19 to treat COVID-19

Small-molecule amplifiers co-translationally increase CFTR mRNA stability through PCBP1 binding

Results from a multicenter phase IIa study of PF-06700841 in patients with plaque psoriasis

Identification of a novel series of 1,6-naphthyridinone-based class II MET kinase inhibitors

CureVac announces positive preclinical data for its coronavirus vaccine candidate

FDA approves Pomalyst for AIDS-related and HIV-negative Kaposi sarcoma

FDA clears IND for LB-1148 in COVID-19-associated pulmonary dysfunction

NantKwest and ImmunityBio to begin phase II study of combination immunotherapy

Phase IIb study of PTI-125 in Alzheimer's disease does not meet primary endpoint

Genenta presents phase I/II data for Temferon cell-based therapy in patients with GBM

First-in-human data for novel proliposomal paclitaxel, TSD-001, in NMIBC

Interim phase II data for apalutamide plus abiraterone acetate/prednisone in prostate cancer

Microbiome modulates effects of ALS mutation

Designer proteins for RSV vaccine

TNFAIP2 identified as potential therapeutic target in platinum-resistant urothelial carcinoma

Medshine Discovery discloses Wee1 inhibitors

Gilead Sciences divulges PD-1/PD-L1 interaction inhibitors

Intra-Cellular Therapies patents PDE2A inhibitors

FronThera US Pharmaceuticals synthesizes new TYK2 inhibitors

Novartis divulges NLRP3 inhibitors

Otoferlin gene therapy restores hearing in congenital deafness model

CCX-140 shows no meaningful reduction in proteinuria in phase II study in FSGS

Opdivo + Yervoy approved in U.S. for first-line metastatic NSCLC with PD-L1 expression >= 1%

FDA grants accelerated approval to Rubraca for BRCA-mutated metastatic CRPC

HPTN 083 interim analysis shows LA cabotegravir highly effective at preventing HIV

FDA approves Qinlock for fourth-line treatment of advanced GIST

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