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BioWorld - Thursday, April 30, 2026
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BioWorld Science
June 16, 2020
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Identification of oral hydroxpyridinone iron chelator for the treatment of iron overload
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"Gastruloids" enable study of embryonic development
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ApoE4's role in Alzheimer's blood vessels
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Neurocrine Biosciences reports positive results with crinecerfont in congenital adrenal hyperplasia
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SARS-CoV-2 neutralizing MAb identified from memory B cells of an individual infected with SARS-CoV
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RemeGen studies RC-88 in phase I for advanced malignant solid tumors
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MT-7117 enters phase III for erythropoietic protoporphyria and X-linked protoporphyria
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[18F]EKZ-001 PET radioligand targeting brain HDAC6: cGMP production and target occupancy in NHPs
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Antisense PNAs targeting lpxB gene inhibit A. baumannii growth and synergize with colistin
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Bayer initiates phase III FINEARTS-HF study of finerenone in heart failure
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First patient dosed in phase II study of ATYR-1923 in COVID-19 with severe respiratory complications
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PDS Biotech and NCI initiate phase II study of PDS-0101
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Pivotal trial of darinaparsin in peripheral T-cell lymphoma meets primary endpoint
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Cue Biopharma advances phase I study of CUE-101 in head and neck cancer
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RICTOR as a new therapeutic target for lung cancer brain metastases
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Phase II data presented from ORIENT-2 study of sintilimab advanced refractory ESCC
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New SHP-2 inhibitors identified at Tuojie Biotech
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Shanghai Pharmaceuticals Holding patents MAPK11 and 14 inhibitors
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New Mnk1 and Mnk2 inhibitors discovered at Shanghai De Novo Pharmatech
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New dual CDK-HDAC inhibitors synthesized at Hangzhou Innogate Pharma
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Janssen discovers compounds active against respiratory syncytial virus
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The Treg-selective long-acting IL-2 variant CUG-252 reduces inflammation in vitro and in vivo
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Favorable safety, pharmacodynamic activity seen with FT-4202 in phase I study
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FDA grants accelerated approval to Zepzelca for metastatic SCLC
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Janssen plans phase II development of JNJ-40411813 for epilepsy
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Phase IIb study of lanifibranor in NASH meets primary and key secondary endpoints
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FDA approves Lyumjev for type 1 and type 2 diabetes
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