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Home » Newsletters » BioWorld Science

BioWorld Science

July 23, 2020

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Mitochondria, interneurons, cognition link explored

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Huntington's disease found to alter neurodevelopment

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TTX-3360 selected as Triplet's first clinical candidate for repeat expansion disorders

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Potent dual orexin OX1/2 receptor antagonist with improved PK profile for insomnia treatment

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Phase Ib/II study of margetuximab + pembrolizumab in HER2-positive gastroesophageal adenocarcinoma

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Characterization of real-time CAH degradation under pH environment of GI tract using microrheology

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SOCS3 as a new therapeutic target in breast cancer

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RO-7297089 demonstrates target engagement and safety in models of MM

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CSF-1R as novel therapeutic target in 4T1 xenografts

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SPV Therapeutics synthesizes new CDK inhibitors

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Chinese investigators patent P2X3 receptor antagonists

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Integral BioSciences discloses IDH1 mutant inhibitors

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Dana-Farber Cancer Institute describes CDK7 inhibitors

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Janssen Pharmaceutica and Johnson & Johnson present FGFR3 inhibitors

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Signs of efficacy seen with DC-based cryoimmunotherapy ACT-2001 in mCRPC

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Harbour BioMed presents CD73-targeting antibody HBM-1007 for immuno-oncology therapy

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FibroGenesis' PneumoBlast induces reduction of lung fibrosis

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New phase I/II trial explores use of DNL-310 for pediatric patients with Hunter's syndrome

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TAK-676 studied alone and with pembrolizumab in new phase I study for advanced solid tumors

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First phase II study of Lyme disease vaccine candidate VLA-15 meets endpoints

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AdAlta begins treatment in phase I study of AD-214 for interstitial lung disease

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Inotrem cleared to begin phase IIa study of nangibotide in patients with COVID-19

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PTC initiates phase II/III study of PTC-299 in hospitalized participants with COVID-19

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Gan & Lee opens phase Ib/II study of GLR-2007 in advanced solid tumors

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UCB begins first-in-human evaluation of UCB-8600

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