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BioWorld Science

Aug. 28, 2020

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Just add fever

Tyme advancing oral synthetic bile acid TYME-19 into clinic for COVID-19

STING agonist JNJ-67544412 shows antitumor activity in syngeneic tumor models

Synthetic synaptic protein restores neuronal connections

CKI-alpha/delta inhibitors disclosed by Bayer, Dana-Farber and The Broad Institute

Novartis discovers deltaF508 mutant CFTR correctors

New neurotensin receptor type 2 agonists patented by Socpra Sciences Sante et Humaines SEC

Medibiofarma identifies new prostanoid EP2 and/or EP4 receptor ligands

ATSO Corp, Cas Biotechnology present antisense oligonucleotides against GST proteins

Interim data from phase I study of 4-1BB antibody ATOR-1017 in advanced cancer

European conditional marketing authorization for Blenrep in relapsed and refractory multiple myeloma

ViiV begins first-in-human study with GSK-3739937 for HIV

Ocellaris opens enrollment in phase Ib/IIa study of OC-001 in locally advanced or metastatic cancers

UCB studies dapirolizumab pegol in phase III for moderate to severely active SLE

PRAK-3202 generates immune response against SARS-Cov-2 antigens in mice

Limited effect on HBsAg seen with JNJ-6379 regimens in phase II HBV study

Lilly begins phase II study of LY-3471851 for SLE

GNE-565: a Nav1.7 inhibitor with oral activity in a mouse model of Nav.17-associated pain

New phase IIa study evaluates AMT-101 in ulcerative colitis

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