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BioWorld Science

Aug. 28, 2020

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Just add fever

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Tyme advancing oral synthetic bile acid TYME-19 into clinic for COVID-19

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STING agonist JNJ-67544412 shows antitumor activity in syngeneic tumor models

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Synthetic synaptic protein restores neuronal connections

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CKI-alpha/delta inhibitors disclosed by Bayer, Dana-Farber and The Broad Institute

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Novartis discovers deltaF508 mutant CFTR correctors

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New neurotensin receptor type 2 agonists patented by Socpra Sciences Sante et Humaines SEC

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Medibiofarma identifies new prostanoid EP2 and/or EP4 receptor ligands

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ATSO Corp, Cas Biotechnology present antisense oligonucleotides against GST proteins

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Interim data from phase I study of 4-1BB antibody ATOR-1017 in advanced cancer

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European conditional marketing authorization for Blenrep in relapsed and refractory multiple myeloma

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ViiV begins first-in-human study with GSK-3739937 for HIV

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Ocellaris opens enrollment in phase Ib/IIa study of OC-001 in locally advanced or metastatic cancers

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UCB studies dapirolizumab pegol in phase III for moderate to severely active SLE

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PRAK-3202 generates immune response against SARS-Cov-2 antigens in mice

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Limited effect on HBsAg seen with JNJ-6379 regimens in phase II HBV study

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Lilly begins phase II study of LY-3471851 for SLE

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GNE-565: a Nav1.7 inhibitor with oral activity in a mouse model of Nav.17-associated pain

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New phase IIa study evaluates AMT-101 in ulcerative colitis

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