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BioWorld - Thursday, December 18, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

Dec. 15, 2020

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Enrollment ongoing in first-in-human study of JNJ-74856665 in AML or MDS

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Phase II study of KN-046 in patients with thymic carcinoma begins

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Aravive opens enrollment in phase Ib/II study of AVB-S6-500 in clear cell renal cell carcinoma

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Missense variants in c-Myc, CDK4 and ARHGDIA genes identified as potential causes of MODY by WES

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CureVac initiates pivotal phase IIb/III study of CVnCoV

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TCR2 presents positive interim data from ongoing phase I/II study of gavo-cel

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ADU-S100 plus pembrolizumab appears well tolerated in recurrent/metastatic HNSCC

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AB-729 results in robust reduction in HBsAg in patients with chronic hepatitis B

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Nuclear receptors protect against kidney disease

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First patient dosed in phase II BLUEPRINT study of BLU-5937

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Arvinas reports interim clinical data for ARV-471 and ARV-110

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FDA clears IND for phase I study of LB-1901 in relapsed or refractory T-cell lymphoma

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Voronoi patents FLT3 and/or MAP4K1 and/or CDK6/cyclin D1 inhibitors

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U.S. researchers synthesize new KRAS mutant inhibitors

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Gilead Sciences identifies MAP4K1 inhibitors

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Poxel presents further phase IIa data for PXL-770 in NASH

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Bolting TLR agonist to antibody converts cold tumors

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InvisiMask human antibody nasal spray protects against SARS-CoV-2 infection in vivo

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BioTheryX presents new GSPT1 inhibitors

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Phase III KESTREL study of Beovu in DME meets primary endpoint

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Suzhou Ribo Life Science describes new PCSK9-targeting siRNA

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Phase II trial examines DS-1062 for advanced or metastatic NSCLC with actionable genomic alterations

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European Commission approves Trixeo Aerosphere for maintenance treatment of COPD

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Mesoblast reports topline phase III data on Revascor in advanced chronic heart failure

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SOD1G93A Grm5+/- mouse model highlights mGlu5 receptors as a target in amyotrophic lateral sclerosis

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FDA approves Klisyri for actinic keratosis on the face or scalp

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TOT Biopharm presents promising phase I data for trastuzumab ADC TAA-013

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