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BioWorld - Sunday, March 15, 2026
Home » Newsletters » BioWorld Science

BioWorld Science

March 31, 2021

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Wave ends clinical development of WVE-120102 and WVE-120101 for Huntington's disease

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New model of MECP2 duplication syndrome may advance antisense oligonucleotide treatment

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Dosing begins in phase I study of DD-01 in obese patients with diabetes and NAFLD

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Pediatric study of CRV-101 against varicella in HIV-positive children approved in South Africa

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FDA approves IND application for phase I study of TJ-CD4B bispecific antibody

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Promising data from first 4 patients treated with BS-01 optogenetic gene therapy

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INSERM and others present monoclonal antibodies targeting IL-20RB

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TaiGen Biotechnology discovers hepatitis B antiviral agents

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Yhhu-2407, novel low systemic DGAT1 inhibitor with potential for the treatment of dyslipidemia

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New agents for encephalitic alphaviruses identified at the Wisconsin Alumni Research Foundation

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The University of Texas System divulges RIP-1 inhibitors

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177Lu-DOTA-EB-TATE is well tolerated and effective in patients with late-stage NETs

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New genetic variants in CD80 found to have prognostic value in prostate cancer

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New SHP-2 inhibitors identified at Sichuan Kelun-Biotech Biopharmaceutical

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Equillium reports data from ongoing phase Ib study of itolizumab in SLE

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China NMPA clears CTA for basket trial of Trodelvy for cancers with high TROP-2 expression

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FDA approves Vyxeos for secondary AML in pediatric patients

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Huyabio signs clinical collaboration agreement for phase III melanoma trial of HBI-8000 with Opdivo

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Squalenoyl siRNA PMP22 nanoparticles developed for Charcot-Marie-Tooth disease type 1 A

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FDA clears initiation of first-in-human study of CRISPR_SCD-001 for sickle cell disease

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Cabometyx with Opdivo approved in E.U. for first-line advanced RCC

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European Commission approves Ontozry for drug-resistant focal-onset seizures in adults

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Disulfiram blocks conformational changes of the complex between human p97 and its cofactor Npl4/Ufd1

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Kamada reports phase I/II topline results on anti-SARS-CoV-2 plasma-derived IgG

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Pivotal topline data on BNT-162b2 in adolescents aged 12-15 years

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ChromaDex announces research initiative to study effects of Niagen and citrin deficiency

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FDA clears IND for phase I/IIa study of AFM-24 with SNK-01 for EGFR-expressing solid tumors

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