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BioWorld - Friday, December 5, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

April 30, 2021

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Boehringer Ingelheim initiates phase I study of BI-1701963 alone or in combination with BI-3011441

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ERX-963 does not improve sleepiness in myotonic dystrophy type 1 patients

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Enrollment opens in phase II/III study of MK-5475 in PAH

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Enrollment opens in first-in-human study of OMO-103 in solid tumors

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Cereno and University of Michigan collaborate on preclinical development of CS-585

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Analysis of immunological and inflammatory factors associated with COVID-19 severity and progression

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Xencor initiates phase I study of XmAb-564 for autoimmune diseases

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X chromosome reactivation widely affects proteome

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New STING receptor antagonists identified at IFM Due

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Molecular Skin Therapeutics describes dual kallikrein 5/7 inhibitors

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PD-1/PD-L1 interaction inhibitors identified at Bristol Myers Squibb

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Recurium IP Holdings patents ERK-1 and/or ERK-2 inhibitors

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Goldfinch Biopharma discovers CDK5 inhibitors

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First clinical trial evaluating intravesical bacteriophage therapy for the treatment of UTIs

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Atogepant statistically reduces monthly migraine days in phase III trial

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First-in-class KAT6A/KAT6B inhibitor PF-9363 shows antitumor activity against ER+ breast cancer

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Phase III NEPTUNO study of plitidepsin in COVID-19 receives authorization in Spain

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PRT-1419 shows potent antitumor activity in preclinical models

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MiR-17-92 as a therapeutic target in lupus nephritis and other autoimmune diseases

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Neuromelanin MRI predicts treatment response in patients with first-episode schizophrenia

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miR-206 is a prognostic marker of LGMDD2 disease progression

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Phase II trial of vonoprazan regimens for H. pylori infection meets endpoints

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Phase IIb/III study of masitinib in metastatic CRPC meets primary endpoint

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Phase II trial evaluates ImmunityBio Anktiva with ART to inhibit HIV reservoirs

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Mesoblast reports 60-day results on remestemcel-L in COVID-19 related ARDS

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Preclinical through phase III, new COVID-19 therapy trials ramp up

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