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BioWorld - Thursday, June 11, 2026
Home » Newsletters » BioWorld Science

BioWorld Science

May 4, 2021

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Lysogene initiates phase I/II study of LYS-GM101 gene therapy in infantile GM1 gangliosidosis

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FDA approves IND for KRAS G12C inhibitor JAB-21822

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SAN-903 reduces lung inflammation and fibrosis in mouse model of IPF

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First direct KRAS G12V(ON) inhibitors developed at Revolution Medicines

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New model allows exploration of PHF21B gene function

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Promising part A data from MOMENTUM study of SRP-5051 in DMD

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Promising safety data from first dose cohort of phase I study evaluating DSG3-CAART

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Shanghai HaiHe Biopharma patents BRD4 inhibitors

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Janssen Biotech presents DHODH inhibitors

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New IDH1 inhibitors presented by Shanghai Meton Pharmaceutical

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Kallyope discloses GPR119 agonists

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Avacta Life Sciences presents new PD-L1 inhibitors

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Topline data presented from first cohort of phase Ib trial of RGLS-4326

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BRM-421: human study data for dry eye syndrome

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Novavax announces pediatric expansion of pivotal PREVENT-19 trial of NVX-CoV-2373

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Ongoing TOGETHER platform study will evaluate Lambda in outpatients with COVID-19

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HORNBILL phase I data reported for BI-764524

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DF-6002 shows robust antitumor activity in preclinical models

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Discovery and optimization of novel N-pyrimidines as IDO1 inhibitors

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Administration of 5,6-DiHETE, an endogenous TRPV4 antagonist, contributes to colitis healing in mice

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Mitochondrial peptide causes septic shock nosocomials, mortality

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LRRK2 inhibitor DNL-151 well tolerated in healthy volunteers and patients with PD

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XBiotech and INSERM collaborate on phase II/III trial of XB-2001

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Vaxart reports phase I findings on oral COVID-19 vaccine VXA-CoV2-1

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FDA clears IND for phase II trial of CT-868 in overweight and obese patients with type 2 diabetes

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FDA approves Kloxxado for opioid overdose

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Merus begins phase I/II study of MCLA-129 in NSCLC and solid tumors

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PXS-5505 to enter preclinical evaluation for glioblastoma

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