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BioWorld Science

May 7, 2021

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Erasca opens enrollment in phase Ib/II study of ERAS-007 in advanced or metastatic solid tumors

Interim data from RUBY study presented for OKG-0301 in AC

Intraocular pressure lowering by soluble guanylate cyclase inhibitor ID-65-CW69 studied in monkeys

Positive 12- and 24-month data reported from ongoing XLRP phase I/II study

Medshine Discovery divulges new CDK inhibitors

Aucentra Therapeutics patents CDK inhibitors

DarwinHealth and Bristol Myers Squibb establish Novel Cancer Target Initiative

IMPACT Therapeutics identifies new Wee1 inhibitors

CB-5083 ameliorates disease pathology in VCP-mutated knock-in mouse model of IBMPFD

Betta Pharmaceuticals synthesizes EGFR inhibitors

Phase II trial shows improved PFS when relacorilant is added to nab-paclitaxel in ovarian cancer

Beijing Dongfang Biotech patents IL-10-containing fusion proteins for cancer

Interim phase II data on miricorilant in NASH show liver fat reductions

ABP-201 for treating angiogenic eye diseases

Discovery and preclinical characterization of novel bifunctional anti-PD-1 x IL-15 proteins

Aslan Pharmaceuticals presents phase I data for the IL13RA1 inhibitor ASLAN-004

Enanta reports data from ongoing phase Ib study of EDP-514 for chronic HBV

Landos initiates phase II study of omilancor in Crohn's disease

Topline phase IIa data reported on FOL-005 for alopecia

China's NMPA gives clinical trial approval for JS-201 for advanced malignancies

China NMPA grants conditional approval to pamiparib for advanced ovarian cancer

Pivotal trial of arimoclomol in ALS does not meet primary and secondary endpoints

Gut microbiome affects protein folding in brain, muscles

PLEK2 as prognostic biomarker and therapeutic target in ESCC

FDA clears IND for Lyndra's LYN-014 for weekly treatment of opioid use disorder

Pivotal study evaluates PD-G-506-A for margin assessment during breast conserving surgery

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