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BioWorld Science

June 7, 2021

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New anti-EGFRvIII antibodies patented by Regeneron Pharmaceuticals

Wuhan Optics Valley Yatai Pharmaceutical Research Institute patents HIF-2-alpha inhibitors

New ROCK1/2 inhibitors identified at Wuhan LL Science and Technology Development Co.

Bayer identifies new PTGER3 antagonists

Taisho Pharmaceutical presents new MMP-2 inhibitors

Optogenetic vector GS030-DP with light stimulation shows promise in retinitis pigmentosa patient

IMC-1 improves multiple fibromyalgia symptoms

Completion of target enrollment in part A of phase I/II study of MRx-4DP0004 in asthma

Surface Oncology and Roche collaborate on immune-oncology study evaluating SRF-388 in HCC

First subjects dosed in phase II study of ADV-110 in Australia

Localized production of protein therapeutics in tumor cells using the SHREAD gene therapy platform

Genome-wide screening identifies shared and specific host factors of SARS-CoV-2 and other CoVs

Boehringer Ingelheim initiates phase I study of BI-765049 alone or in combination with BI-754091

Sorrento Therapeutics and Karolinska Institutet collaborate on iPSC-derived DAR-NK cells

BTK-selective degrader NX-5948 reduces inflammation in a murine model of rheumatoid arthritis

China's NMPA clears IND for FXR agonist ASC-42 for chronic hepatitis B

Enrollment begins in phase I study of RO-7300490 as single agent or in combination with atezolizumab

New phase I/II study evaluates AGuIX gadolinium-based nanoparticles in pancreatic and lung cancers

JMT-103 shows safety and efficacy in phase Ib/II study in patients with giant cell tumor of bone

Cardiac troponin I has predictive potential for ICU admission and mortality in COVID-19 patients

Noncovalent approach using monobodies selectively recognizes and inhibits oncogenic RAS mutants

Initial first-in-human data presented for TNO-155

New PPARgamma agonist shows promise in neurodegenerative diseases

FDA issues clinical hold letter for Ortho Regenerative Technologies' ORTHO-R

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