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BioWorld Science

Aug. 17, 2021

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Aberrant NAD+ metabolism underlies Zika microcephaly

Phase II study initiated to assess aspacytarabine in AML and MDS patients

Moderna initiates phase I/II study of mRNA-3705 for methylmalonic acidemia

Chengdu Biobel patents compounds for C. difficile infection

Chinese researchers divulge new PD-1/PD-L1 interaction inhibitors

Jasan Bio Medicine (Jiaxing) synthesizes new DHFR inhibitors

Clinical trial finds PRAX-114 improves symptoms of perimenopausal depression

AgeX Therapeutics describes new exosomes for wound healing

Neurodevelopmental disorders tied to genetic variation in CLCN3 gene

Inhibitors of TNF-alpha- and IL-6-induced adhesion show activity in IBD models

BBP-631 enters phase I/II for treating congenital adrenal hyperplasia

Initiation of phase II trial to assess TLX-66 for pediatric leukemia

Phase II study cleared to evaluate TQ Formula in COVID-19 patients

TRIDENT-2 study evaluates repotrectinib combined with trametinib in KRAS G12D mutant solid tumors

IND application accepted for phase I/Ib trial for CPI-818 for treating R/R T-cell lymphoma in China

Crovalimab evaluated for vaso-occlusive episodes in patients with sickle cell disease

Green light for censavudine to initiate phase II trial in neurodegeneration

Transient nanofibrillar hydrogels release glucagon under low-glucose conditions

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