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BioWorld Science

Aug. 17, 2021

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Aberrant NAD+ metabolism underlies Zika microcephaly

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Phase II study initiated to assess aspacytarabine in AML and MDS patients

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Moderna initiates phase I/II study of mRNA-3705 for methylmalonic acidemia

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Chengdu Biobel patents compounds for C. difficile infection

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Chinese researchers divulge new PD-1/PD-L1 interaction inhibitors

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Jasan Bio Medicine (Jiaxing) synthesizes new DHFR inhibitors

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Clinical trial finds PRAX-114 improves symptoms of perimenopausal depression

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AgeX Therapeutics describes new exosomes for wound healing

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Neurodevelopmental disorders tied to genetic variation in CLCN3 gene

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Inhibitors of TNF-alpha- and IL-6-induced adhesion show activity in IBD models

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BBP-631 enters phase I/II for treating congenital adrenal hyperplasia

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Initiation of phase II trial to assess TLX-66 for pediatric leukemia

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Phase II study cleared to evaluate TQ Formula in COVID-19 patients

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TRIDENT-2 study evaluates repotrectinib combined with trametinib in KRAS G12D mutant solid tumors

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IND application accepted for phase I/Ib trial for CPI-818 for treating R/R T-cell lymphoma in China

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Crovalimab evaluated for vaso-occlusive episodes in patients with sickle cell disease

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Green light for censavudine to initiate phase II trial in neurodegeneration

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Transient nanofibrillar hydrogels release glucagon under low-glucose conditions

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