BioWorld - Thursday, December 18, 2025

BioWorld Science

Feb. 18, 2022

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Extracellular domains are not effective targets to disrupt intracellular HER2-HER3 tumor signaling

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CECR2 promotes breast cancer metastasis through NF-kappaB signaling and immunosuppression

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Neumora licenses rights to novel M4 receptor PAMs from Vanderbilt for schizophrenia

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Monoclonal antibodies in AR-701 cocktail neutralize SARS-CoV-2 Omicron variant

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New coagulation factor XIa inhibitors synthesized at Janssen Pharmaceutica

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Merck & Co. presents new adenosine A2A and/or A2B receptor antagonists

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New SREBP inhibitors identified at Capulus Therapeutics

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Fog Pharmaceuticals describes stapled peptides targeting beta-catenin

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New HSD17B13 inhibitors identified at Inipharm

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Neurophilin-1 is an inhibitor of HIV-1 infectivity

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Broadly neutralizing HCV antibodies isolated from high responders used to design new antibody

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Using photoactivatable peptide toxins for modulation of voltage-gated ion channels

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Nrf2 agonists ameliorate anemia of inflammation by disrupting the hepcidin-ferroportin axis

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Targeting GDNF may have potential to treat IBD

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New biomarkers identified to predict response to vedolizumab in patients with Crohn's disease

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Targeting PFKFB3 reduces the severity of colitis in mouse models

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EBV antibodies put to good use through retargeting

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Mindset reports new benchmarking data on first-generation psychedelics

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Repertoire Immune Medicines and UMass Chan collaborate to understand immune causes of vitiligo

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