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Mon, May 19, 2025

Antibody

Home » Topics » Drugs » Antibody
  • May 16, 2025
    By Brian Orelli

    Therini Bio locks in another $39M for its fibrin-targeting immunotherapies

    Therini Bio raised an additional $39 million in its series A financing round, bringing the total for the round to $75 million. The capital will be used to advance its fibrin-targeting immunotherapies for neurodegenerative diseases.
  • Antibodies attacking cancer cell
    May 15, 2025

    New anti-CCR8 immuno-oncology antibodies with unique binding/pharmacology

    CCR8 is highly expressed on immunosuppressive regulatory T cells (Tregs) in various solid tumors, making it a potential target to enhance antitumor immunity and the efficacy of cancer therapies, including checkpoint inhibitors. However, the impact of CCR8 expression on the Treg phenotype and its role in cancer progression remain unclear.
  • Acute myeloid leukemia
    May 12, 2025

    The humanized antibody hu128.1 targeting TfR1 shows preclinical potential for erythroleukemia

    A recent study explored the therapeutic potential of hu128.1, a humanized antibody targeting transferrin receptor 1 (TfR1), in treating erythroleukemia using xenograft mouse models. The results demonstrate that hu128.1 exerts strong antitumor activity against human erythroleukemic (ERY-1) cells, highlighting its promise as a candidate for managing this aggressive cancer.
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