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BioWorld - Wednesday, July 6, 2022
Home » Topics » Drugs » Antibody

Antibody
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Boehringer Ingelheim to develop A*STAR antibodies for targeted cancer therapies

June 14, 2022
By David Ho
No Comments
Singapore’s Agency for Science, Technology and Research (A*STAR) has inked a deal with Boehringer Ingelheim GmbH to develop and commercialize targeted cancer therapies.
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Boehringer Ingelheim to develop A*STAR antibodies for targeted cancer therapies

June 10, 2022
By David Ho
No Comments
Singapore’s Agency for Science, Technology and Research (A*STAR) has inked a deal with Boehringer Ingelheim GmbH to develop and commercialize targeted cancer therapies.
Read More
Antibodies attacking cancer cell

Sanofi aims to tweak oncology antibodies, signing $2.5B R&D deal with Adagene

March 8, 2022
By Richard Staines
No Comments
Adagene Inc. has announced a research collaboration with Sanofi SA, to find “masked” monoclonal and bispecific antibodies that are safer than marketed drugs in oncology, in a deal worth up to $2.5 billion plus royalties. San Diego and Suzhou, China-based Adagene will generate masked versions of Sanofi antibodies, taking responsibility for early stage research activities using its Safebody technology.
Read More
Antibodies attacking cancer cell

Sanofi aims to tweak oncology antibodies, signing $2.5B R&D deal with Adagene

March 2, 2022
By Richard Staines
No Comments
Adagene Inc. has announced a research collaboration with Sanofi SA, to find “masked” monoclonal and bispecific antibodies that are safer than marketed drugs in oncology, in a deal worth up to $2.5 billion plus royalties. San Diego and Suzhou, China-based Adagene will generate masked versions of Sanofi antibodies, taking responsibility for early stage research activities using its Safebody technology. Sanofi will be responsible for later-stage research and all clinical, product development and marketing activities.
Read More
Microscopic visualization of a cancerous cell

EBV antibodies put to good use through retargeting

Feb. 22, 2022
By Anette Breindl
No Comments
Researchers at Inserm have developed a method to direct pre-existing antibodies toward new targets. Their bimodular fusion proteins could be a broadly useful method for expanding access to antibody therapy. In a study that appeared in the Feb. 11, 2022, issue of Science Advances, the teams showed that antibodies to Epstein-Barr virus (EBV), which are present in 95% of the global population, could be redirected to a target cell of their choosing by fusing an EBV antigen to a cellular targeting ligand.
Read More
Microscopic visualization of a cancerous cell

EBV antibodies put to good use through retargeting

Feb. 18, 2022
By Anette Breindl
No Comments
Researchers at Inserm have developed a method to direct pre-existing antibodies toward new targets. Their bimodular fusion proteins could be a broadly useful method for expanding access to antibody therapy. In a study that appeared in the Feb. 11, 2022, issue of Science Advances, the teams showed that antibodies to Epstein-Barr virus (EBV), which are present in 95% of the global population, could be redirected to a target cell of their choosing by fusing an EBV antigen to a cellular targeting ligand.
Read More
IPO, coins, financial chart

Mabwell raises ¥3.48B in Shanghai IPO, though shares meet cool reception

Jan. 25, 2022
By Doris Yu
No Comments
Mabwell Bioscience Co. Ltd. raised ¥3.48 billion ($547.9 million) in a Shanghai STAR Market IPO on Jan. 18 to support company R&D efforts and plans to build an antibody production plant. Though oversubscribed, the offering got a cool market reception, with shares plunging nearly 30% from a ¥32 open (US$27.96), then closing at ¥24.50 on the first day of trading before recovering slightly to ¥27.40 on Jan. 20.
Read More
IPO, coins, financial chart

Mabwell raises ¥3.48B in Shanghai IPO, though shares meet cool reception

Jan. 20, 2022
By Doris Yu
No Comments
Mabwell Bioscience Co. Ltd. raised ¥3.48 billion ($547.9 million) in a Shanghai STAR Market IPO on Jan. 18 to support company R&D efforts and plans to build an antibody production plant. Though oversubscribed, the offering got a cool market reception, with shares plunging nearly 30% from a ¥32 open (US$27.96), then closing at ¥24.50 on the first day of trading before recovering slightly to ¥27.40 on Jan. 20.
Read More
Parkinson's disease illustration showing neurons containing alpha-synuclein

Sanofi in-licenses ABL Bio Parkinson’s drug for $1B as alpha-synuclein research heats up

Jan. 18, 2022
By Richard Staines
No Comments
Targeting the toxic alpha-synuclein protein found in the brains of people with Parkinson’s is one of the most promising approaches to treat the disease in the clinic – but getting any drug into the brain is a challenge. Sanofi SA has joined with ABL Bio Inc. to solve this problem, in-licensing ABL-301, a preclinical bispecific antibody that locks on to misfolded alpha-synuclein but also includes a molecular “shuttle” that allows it to penetrate the blood-brain barrier.
Read More
Parkinson's disease illustration showing neurons containing alpha-synuclein

Sanofi in-licenses ABL Bio Parkinson’s drug for $1B as alpha-synuclein research heats up

Jan. 12, 2022
By Richard Staines
No Comments
Targeting the toxic alpha-synuclein protein found in the brains of people with Parkinson’s is one of the most promising approaches to treat the disease in the clinic – but getting any drug into the brain is a challenge. Sanofi SA has joined with ABL Bio Inc. to solve this problem, in-licensing ABL-301, a preclinical bispecific antibody that locks on to misfolded alpha-synuclein but also includes a molecular “shuttle” that allows it to penetrate the blood-brain barrier.
Read More
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