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Home » Topics » Drugs » Antibody

Antibody
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Brain illustrated with pills
Neurology/psychiatric

Disease-modifying Alzheimer’s drugs are ‘drivers of change’

March 28, 2025
By Nuala Moran
The first disease modifying therapies for Alzheimer’s may have limited utility in some senses, but they will be a force for change, providing momentum and altering the way governments as payers, and health systems as carers, think about the disease.
Read More

Come what May: Equillium marches on with itolizumab in GVHD

March 27, 2025
By Randy Osborne
Equillium Inc. is forging ahead with regulatory plans for itolizumab in first-line treatment of patients with acute graft-vs.-host disease (GVHD), despite a phase III disappointment. Shares of the La Jolla, Calif.-based firm (NASDAQ:EQ) closed March 27 at 46 cents, down 29 cents, or 39%, on top-line data from the Equator study testing itolizumab, which is designed to target the CD6-ALCAM signaling pathway.
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Brain illustrated with pills
Neurology/psychiatric

Disease-modifying Alzheimer’s drugs are ‘drivers of change’

March 27, 2025
By Nuala Moran
The first disease modifying therapies for Alzheimer’s may have limited utility in some senses, but they will be a force for change, providing momentum and altering the way governments as payers, and health systems as carers, think about the disease.
Read More
Brain illustrated with pills

Disease-modifying Alzheimer’s drugs are ‘drivers of change’

March 26, 2025
By Nuala Moran
The first disease modifying therapies for Alzheimer’s may have limited utility in some senses, but they will be a force for change, providing momentum and altering the way governments as payers, and health systems as carers, think about the disease.
Read More
IV drips

Taimed’s long-acting HIV treatment offers daily ART alternative

March 25, 2025
By Tamra Sami
Taimed Biologics Inc.’s TMB-365/TMB-380 long-acting combination of broadly neutralizing antibodies regimen for HIV maintenance could reshape HIV treatment management, offering a viable alternative to daily combination antiretroviral therapy (cART), the Taipei-based company said after reporting on phase IIa results.
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Newco news

Hillstar launches with $67M series A to target TRBV9+ T cells

March 25, 2025
By Brian Orelli
Hillstar Bio came out of stealth mode, announcing a $67 million series A financing round with investors including Droia Ventures, Frazier Life Sciences, Novo Holdings A/S and Lifearc Ventures.
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Antibodies attacking virus cell
Immune

Astrazeneca enters multispecific antibody collaborations with CEPI, Harbour Biomed

March 21, 2025
CEPI is partnering with Astrazeneca plc to advance VHH-based multispecific antibodies targeting influenza, while Harbour Biomed Ltd. has entered into a global strategic collaboration with Astrazeneca to discover and develop next-generation multispecific antibodies for immunology, oncology and other diseases.
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IV drips

Taimed’s long-acting HIV treatment offers daily ART alternative

March 20, 2025
By Tamra Sami
Taimed Biologics Inc.’s TMB-365/TMB-380 long-acting combination of broadly neutralizing antibodies regimen for HIV maintenance could reshape HIV treatment management, offering a viable alternative to daily combination antiretroviral therapy (cART), the Taipei-based company said after reporting on phase IIa results.
Read More
Black dollar sign on ombre blue background

Dren draws $600M up front from Sanofi in $1.9B antibody deal

March 20, 2025
By Lee Landenberger
Sanofi SA is getting deeper into oncology and immunology therapy development through buying Dren Bio Inc.’s myeloid cell engager for deep B-cell depletion, DR-0201. The deal could reach as high as $1.9 billion for privately held Dren. Sanofi is paying a hefty $600 million up front, and milestone payments to come could add up to $1.3 billion.
Read More
Antibodies attacking cancer cell

Oxford Bio signs with Roche for $1B+ antibody research program

March 19, 2025
By Nuala Moran
Oxford Biotherapeutics Ltd. is partnering with Roche AG to expand the current field of tumor antigens that can be drugged with antibodies, as part of a potential $1 billion-plus agreement. The agreement will see Oxford Biotherapeutics apply its membrane protein discovery platform to search for novel cancer cell antigens, which will be validated through the research collaboration, with Roche then taking the lead in advancing any resulting antibody programs.
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