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Home » Topics » Drugs » Antibody

Antibody
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Man piecing together a puzzle
Neurology/psychiatric

Bristol Myers Squibb licenses Bioarctic’s Aβ antibody program

Dec. 20, 2024
Bioarctic AB has entered into a global exclusive license agreement with Bristol Myers Squibb Co. for Bioarctic’s pyroglutamate-amyloid-β (Aβ) antibody program.
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Radiotherapy of cancer

SK Biopharma, Proen team up to develop new radiopharmaceuticals

Dec. 17, 2024
By Marian (YoonJee) Chu
SK Biopharmaceuticals Co. Ltd. and Proen Therapeutics Co. Ltd. joined hands in a research collaboration to advance up to two preclinical small protein-based radiopharmaceuticals by 2027 – the year SK Biopharmaceuticals aims to “become a leading radiopharma player” worldwide.
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Jury convicts biotech execs in fraud scheme

Dec. 11, 2024
By Mari Serebrov
Nearly three years after being terminated as president and CEO of Cytodyn Inc., Nader Pourhassan was convicted June 9 by a U.S. federal jury for his role in a securities fraud scheme to deceive investors about the Vancouver, Wash.-based company’s development of leronlimab. The jury also convicted Kazem Kazempour, the CEO of Amarex Clinical Research LLC, a contract research organization hired by Cytodyn, for his part in the scheme.
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Immuno-oncology

Pilatus Biosciences’ PLT-012 awarded orphan drug designation

Dec. 11, 2024
Pilatus Biosciences Inc.’s PLT-012 has been awarded orphan drug designation by the FDA for treating liver and intrahepatic bile duct cancer.
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Immune

S-4321, a dual-cell bidirectional antibody that agonizes inhibitory receptors at the T cell-APC synapse

Dec. 4, 2024
Seismic Therapeutic Inc. has provided preclinical data for S-4321, a novel dual-cell bidirectional (DcB) PD-1:FcγRIIb antibody being developed for the treatment of autoimmune disease.
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Mast cell releasing histamine during allergic response
Immune

Longbio’s LP-003 receives NMPA clearance to enter clinic for food allergy

Nov. 26, 2024
Longbio Pharma (Suzhou) Co. Ltd. has obtained IND approval from China’s National Medical Products Administration (NMPA) for LP-003, the company’s next-generation anti-IgE antibody, to enter a clinical trial for the treatment of food allergy.
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Antibodies illustration
Inflammatory

Asahi Kasei Pharma licenses rights to Chiome’s humanized anti-CX3CR1 antibody

Nov. 22, 2024
Chiome Bioscience Inc. and Asahi Kasei Pharma Corp. have entered into an exclusive license agreement to develop and commercialize Chiome’s humanized anti-CX3CR1 antibody, PFKR, currently in the preclinical stage.
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Illustration of cancer in the bile ducts

FDA approves biliary tract cancer treatment from Jazz

Nov. 21, 2024
By Lee Landenberger
More than a week ahead of its priority PDUFA date, the U.S. FDA has greenlit the first dual HER2-targeted bispecific antibody specifically for previously treated, unresectable or metastatic HER2-positive biliary tract cancer. The approval went to Jazz Pharmaceuticals plc for Ziihera (zanidatamab), an injection given to adults every two weeks. The treatment was designed to have a more favorable profile than competitors, where drugs targeting HER2 such as Astrazeneca plc’s Enhertu (trastuzumab deruxtecan) and Roche Holding AG’s Herceptin (trastuzumab) are options, as well as checkpoint inhibitors such as Merck & Co Inc.’s Keytruda (pembrolizumab).
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Chinese flag and microscopes
Drug design, drug delivery & technologies

‘A decade of innovation, a decade to come’ for China pharma

Nov. 19, 2024
By Marian (YoonJee) Chu
As China rises to second place, next only to the U.S., for innovative new drugs, a new report by Clarivate – A Decade of Innovation, A Decade to Come – outlines key policy reforms and regulatory, R&D and investment trends driving past and future growth of Chinese biopharmaceuticals.
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Digital handshake

Biosion sells antibody rights to Aclaris in $940M deal

Nov. 18, 2024
By Lee Landenberger
Biosion Inc. is getting more than $40 million in cash up front from Aclaris Therapeutics Inc. for the rights to develop two antibodies. The regulatory and sales milestones could also bring Biosion another $900 million. The two assets are BSI-045B, a high affinity and high potency anti-TSLP monoclonal antibody, and BSI-502, a bispecific antibody directed against TSLP and IL4R.
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