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Home » Topics » Drugs » Antibody

Antibody
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Illustration of cancer in the bile ducts

FDA approves biliary tract cancer treatment from Jazz

Nov. 21, 2024
By Lee Landenberger
More than a week ahead of its priority PDUFA date, the U.S. FDA has greenlit the first dual HER2-targeted bispecific antibody specifically for previously treated, unresectable or metastatic HER2-positive biliary tract cancer. The approval went to Jazz Pharmaceuticals plc for Ziihera (zanidatamab), an injection given to adults every two weeks. The treatment was designed to have a more favorable profile than competitors, where drugs targeting HER2 such as Astrazeneca plc’s Enhertu (trastuzumab deruxtecan) and Roche Holding AG’s Herceptin (trastuzumab) are options, as well as checkpoint inhibitors such as Merck & Co Inc.’s Keytruda (pembrolizumab).
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Chinese flag and microscopes
Drug design, drug delivery & technologies

‘A decade of innovation, a decade to come’ for China pharma

Nov. 19, 2024
By Marian (YoonJee) Chu
As China rises to second place, next only to the U.S., for innovative new drugs, a new report by Clarivate – A Decade of Innovation, A Decade to Come – outlines key policy reforms and regulatory, R&D and investment trends driving past and future growth of Chinese biopharmaceuticals.
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Digital handshake

Biosion sells antibody rights to Aclaris in $940M deal

Nov. 18, 2024
By Lee Landenberger
Biosion Inc. is getting more than $40 million in cash up front from Aclaris Therapeutics Inc. for the rights to develop two antibodies. The regulatory and sales milestones could also bring Biosion another $900 million. The two assets are BSI-045B, a high affinity and high potency anti-TSLP monoclonal antibody, and BSI-502, a bispecific antibody directed against TSLP and IL4R.
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Chinese flag and microscopes

‘A decade of innovation, a decade to come’ for China pharma

Nov. 18, 2024
By Marian (YoonJee) Chu
As China rises to second place, next only to the U.S., for innovative new drugs, a new report by Clarivate – A Decade of Innovation, A Decade to Come – outlines key policy reforms and regulatory, R&D and investment trends driving past and future growth of Chinese biopharmaceuticals.
Read More
Immuno-oncology

Elpiscience designs fusion protein consisting of NKG2A antibody conjugated to IL-2 mutant

Nov. 18, 2024
Researchers from Elpiscience Biopharmaceuticals Inc. discussed the discovery and preclinical characterization of a novel NKG2A antibody-IL-2 mutant fusion protein – ES-015.129 – being developed as cancer immunotherapy.
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Intestine
Gastrointestinal

Numab and Kaken Pharmaceutical sign agreement for ND-081 for inflammatory bowel disease

Nov. 15, 2024
Numab Therapeutics AG and Kaken Pharmaceutical Co. Ltd. have signed a new collaboration and option agreement to develop ND-081, a multispecific antibody for the treatment of inflammatory bowel disease.
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3D representation of tumor microenvironment
Immuno-oncology

Trispecific antibody CS-2009 has in vivo activity

Nov. 13, 2024
Cstone Pharmaceuticals Co. Ltd. presented preclinical data of CS-2009, a trispecific antibody targeting PD-1, CTLA-4 and VEGF-A, for cancer immunotherapy.
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Unveiling ceremony for the Guangzhou Institutes of Biomedicine and Health and the Maruice Wilkins Joint Center for Biomedicine

Chinese, New Zealand researchers advance new FGFR inhibitor

Nov. 12, 2024
By Tamra Sami
University of Auckland senior research fellow Jeff Smaill first visited China in 2012 as part of a team of 15 scientists from the Maurice Wilkins Center, one of New Zealand’s centers of excellence, to meet with scientists at the Guangzhou Institute of Medicine and Health to find partners to collaborate on drug development projects. The scientists started collaborating that year, and the first project is already in phase I trials in China. It was a joint discovery and development partnership from the beginning, he said.
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Unveiling ceremony for the Guangzhou Institutes of Biomedicine and Health and the Maruice Wilkins Joint Center for Biomedicine

Chinese, New Zealand researchers advance new FGFR inhibitor

Nov. 8, 2024
By Tamra Sami
University of Auckland senior research fellow Jeff Smaill first visited China in 2012 as part of a team of 15 scientists from the Maurice Wilkins Center, one of New Zealand’s centers of excellence, to meet with scientists at the Guangzhou Institute of Medicine and Health to find partners to collaborate on drug development projects. The scientists started collaborating that year, and the first project is already in phase I trials in China. It was a joint discovery and development partnership from the beginning, he said.
Read More
Immune

Oblenio to develop tri-specific T-cell engager for autoimmune diseases

Nov. 7, 2024
Aditum Bio Management Company LLC and Nanjing Leads Biolabs Co. Ltd. have announced the creation of Oblenio Bio.
Read More
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