SAN DIEGO – Despite four decades of clinical research in acute myeloid leukemia (AML), the current standard-of-care induction therapy remains the 7 + 3 regimen, usually referring to seven days of cytarabine plus three days of daunorubicin, based on an initial paper published in 1973, said Harry Erba, during a Saturday media briefing at the American Society of Hematology (ASH) meeting.