Among the 100 IOM-named healthcare services in line for comparative effectiveness research, these were in the top 25 (which were not ranked in any particular order):

Treatments (assistive listening devices, cochlear implants, electric-acoustic devices, habilitation and rehabilitation) for hearing loss in children and adults.

Prevention methods, such as exercise and balance training, versus clinical treatments in preventing falls in older adults.

Upper endoscopy use and frequency for patients with gastroesophageal reflux disease.

Dissemination and translation techniques to facilitate the use of CER by patients, clinicians, payers and others.

Comprehensive care coordination programs, such as the medical home (a model of delivering primary care).

The use of biologics in the treatment algorithm for inflammatory diseases, including Crohn's disease, ulcerative colitis, rheumatoid arthritis and psoriatic arthritis.

Screening, prophylaxis and treatment interventions in eradicating methicillin resistant Staphylococcus aureus (MRSA).

Strategies (bio-patches, reducing central line entry, chlorhexidine for all line entries, antibiotic impregnated catheters, treating all line entries via a sterile field) for reducing healthcare associated infections.

Management strategies for localized prostate cancer.

Low back pain without neurological deficit or spinal deformity.

Alternative detection and management strategies for dementia.

Managing behavioral disorders in people with Alzheimer's disease and other dementias in home and institutional settings.

School-based interventions (meal programs, vending machines and physical education) to combat overweight and obesity.

Social interventions to prevent obesity, hypertension, diabetes and heart disease in at-risk populations.

Management strategies for ductal carcinoma in situ.

Imaging technologies in diagnosing, staging and monitoring patients with cancer.

Genetic and biomarker testing and usual care in preventing and treating breast, colorectal, prostate, lung and ovarian cancer.

Delivery models (primary care, dental offices, schools, mobile vans) to prevent dental caries in children.

Primary care treatment strategies for attention deficit hyperactivity disorder in children.

Wraparound home and community-based services and residential treatment in managing serious emotional disorders in children and adults.

Interventions to reduce health disparities in cardiovascular disease, diabetes, cancer, musculoskeletal diseases and birth outcomes.

Literacy-sensitive disease management programs.

Clinical interventions (prenatal care, nutritional counseling, smoking cessation, substance abuse treatment, and combinations of these interventions) to reduce incidences of infant mortality, pre-term births and low birth rates.

Strategies for preventing unintended pregnancies.

— Lynn Yoffee