Among the 100 IOM-named healthcare services in line for comparative effectiveness research, these were in the top 25 (which were not ranked in any particular order):
• Treatments (assistive listening devices, cochlear implants, electric-acoustic devices, habilitation and rehabilitation) for hearing loss in children and adults.
• Prevention methods, such as exercise and balance training, versus clinical treatments in preventing falls in older adults.
• Upper endoscopy use and frequency for patients with gastroesophageal reflux disease.
• Dissemination and translation techniques to facilitate the use of CER by patients, clinicians, payers and others.
• Comprehensive care coordination programs, such as the medical home (a model of delivering primary care).
• The use of biologics in the treatment algorithm for inflammatory diseases, including Crohn's disease, ulcerative colitis, rheumatoid arthritis and psoriatic arthritis.
• Screening, prophylaxis and treatment interventions in eradicating methicillin resistant Staphylococcus aureus (MRSA).
• Strategies (bio-patches, reducing central line entry, chlorhexidine for all line entries, antibiotic impregnated catheters, treating all line entries via a sterile field) for reducing healthcare associated infections.
• Management strategies for localized prostate cancer.
• Low back pain without neurological deficit or spinal deformity.
• Alternative detection and management strategies for dementia.
• Managing behavioral disorders in people with Alzheimer's disease and other dementias in home and institutional settings.
• School-based interventions (meal programs, vending machines and physical education) to combat overweight and obesity.
• Social interventions to prevent obesity, hypertension, diabetes and heart disease in at-risk populations.
• Management strategies for ductal carcinoma in situ.
• Imaging technologies in diagnosing, staging and monitoring patients with cancer.
• Genetic and biomarker testing and usual care in preventing and treating breast, colorectal, prostate, lung and ovarian cancer.
• Delivery models (primary care, dental offices, schools, mobile vans) to prevent dental caries in children.
• Primary care treatment strategies for attention deficit hyperactivity disorder in children.
• Wraparound home and community-based services and residential treatment in managing serious emotional disorders in children and adults.
• Interventions to reduce health disparities in cardiovascular disease, diabetes, cancer, musculoskeletal diseases and birth outcomes.
• Literacy-sensitive disease management programs.
• Clinical interventions (prenatal care, nutritional counseling, smoking cessation, substance abuse treatment, and combinations of these interventions) to reduce incidences of infant mortality, pre-term births and low birth rates.
• Strategies for preventing unintended pregnancies.
— Lynn Yoffee