One of the stumbling blocks is that “[w]e are still relying on a paradigm of diagnosis” that came into being 200 years ago. “The premise of PM is that the old paradigm is no longer sufficient.”

Harvey Fineberg, MD, president of the Institute of Medicine (IOM; Washington) speaking about the need for the U.S. to widely adopt personalized medicine into its healthcare system, “Boosters of personalized medicine wary of hyperbole, public backlash,” pp. 1, 9.