I. COMMENCED TRADING IN JANUARY
Company (Symbol)# Date Filed Date Comm. Shares/Units (M) Price Shares Out (M)@ Lead, Other Underwriters Gross (US$M) Post-Offering Market Cap (M)%

INITIAL OFFERINGS
There were no initial public offerings that commenced in January.
Total: $0M
Number of IPOs in January: 0
Average value of January IPOs: $0
Number of IPOs in 2008: 0
Total raised in IPOs in 2008: $0M
Average value of IPOs in 2008: $0M
FOLLOW-ON OFFERINGS
Company (Symbol)# Date Filed Date Comm. Shares/Units (M) Price Shares Out (M)@ Lead, Other Underwriters Gross (M) Post-Offering Market Cap (M)%

Orexigen Therapeutics Inc. (OREX)1 1/7/08 1/24/08 7S $11 34 Merrill Lynch & Co.
Leerink Swann LLC (co-lead)
JMP Securities LLC
Lazard Capital Markets
Canaccord Adams Inc.
Natixis Bleichroeder Inc.
$77 $374
Seattle Genetics Inc. (SGEN)2 12/11 1/18 11.5S $9 79 JP Morgan Securities
UBS Investments (co-lead)
RBC Capital Markets
Needham & Co. LLC
William Blair & Co. LLC
$103.5 $711
Targacept Inc. (TRGT)3 7/20 1/17 4.37S $7.07 24.9 Deutsche Bank Sec.
Lazard Capital Markets
Oppenheimer & Co. Inc.
Pacific Growth Equities
$30.9 $176.0
Theratechnologies Inc. (Canada; TSX:TH)4 1/29 1/31 3.5S C$8.50
($8.48)
N/A BMO Capital Markets C$29.8
($29.7)
N/A
Theravance Inc. (THRX)5 1/16 1/17 Notes $25.87 per share N/A Merrill Lynch & Co.
Goldman, Sachs & Co.
$172.5 N/A
Total: $413.6M
Number of follow-on offerings in January: 5
Average value of January follow-ons: $82.72M
Number of follow-on offerings in 2008: 5
Total raised in follow-ons in 2008: $413.6M
Average value of follow-ons in 2008: $82.72M

Notes:
# Unless otherwise indicated, shares are traded on the Nasdaq exchange.
@ This column reflects the shares outstanding following the offering, when disclosed.
% Market capitalization is calculated based on the offering price.
Currency conversions are based on exchange rates at the time of the deal.
TSX = Toronto Stock Exchange.
1 Orexigen's overallotment option: 1.05M shares.
2 Includes Seattle Genetics' overallotment option: 1.5M shares.
3 Includes Targacept's overallotment option: 570,000 shares.
4 Theratechnologies' overallotment option: 350,000 common shares.
5 Includes Theravance's overallotment option: $22.5M in notes.
II. FILED AND PENDING
Company (Symbol/Proposed Symbol)#* Date Filed Shares/Units (M) Price Range Shares Out (M)@ Lead, Other Underwriters Value (M)

INITIAL OFFERINGS
Aegerion Pharmaceuticals Inc. (AEGR) 11/21/07 N/A N/A N/A Piper Jaffray
Thomas Weisel Partners (co-lead)
Lazard Capital Markets
Collins Stewart LLC
$86
Anacor Pharmaceuticals Inc. (ANAC) 8/31/07 N/A N/A N/A Morgan Stanley & Co. Inc.
Cowen & Co. LLC (co-lead)
Pacific Growth Equities LLC
Needham & Co. LLC
$57.5
Archemix Corp. (ARCH) 7/25/07 N/A N/A N/A Banc of America Securities
Bear, Stearns & Co. Inc.
Cowen and Co.
$69
Bayhill Therapeutics Inc. (BHTX) 1/9/08 N/A N/A N/A Pacific Growth Equities LLC
Lazard Capital Markets
Merriman Curhan Ford & Co.
Punk, Ziegel & Co.
$86
Bioheart Inc. (BHRT)1 2/13/07 1S $6-$8 14.35 Merriman, Curhan Ford & Co.
Dawson James Securities (co-lead)
$7
Biolex Inc. (BLEX) 8/14/07 N/A N/A N/A Lehman Brothers Inc.
Deutsche Bank Securities (co-lead)
Leerink Swann & Co. Inc.
$70
Chemocentryx Inc. (CCXI) 11/12/07 N/A N/A N/A Credit Suisse Securities LLC
Cowen and Co.
Leerink Swann
Lazard Capital Markets
$57.5
Elixir Pharmaceuticals Inc. (ELXR) 9/24/07 5S $14-$16 143.5 Credit Suisse Securities LLC
Pacific Growth Equities
Leerink Swann LLC
$75
Insys Therapeutics Inc. (INRX) 8/20/07 N/A N/A N/A Banc of America Securities
UBS Investment Bank (co-lead)
JMP Securities
Natixis Bleichroeder
$86.25
Light Sciences Oncology Inc. (LSON) 4/21/06 5.25S $14-$16 18.5 Cowen & Co.
Wachovia Securities (co-lead)
Jefferies & Co.
Thomas Weisel Partners
$78.75
MonoSol Rx Inc. (MSRX) 5/14/07 4S $16-$18 15 Cowen and Co.
CIBC World Markets
Susquehanna Financial
$68
Omeros Corp. (OMER) 1/10/08 N/A N/A N/A Deutsche Bank Securities
Pacific Growth Equities
Leerink Swann LLC
Needham & Co. LLC
$115
Peplin Inc. (PLIN) 8/10/07 N/A N/A N/A Merrill Lynch & Co.
Cowen & Co. LLC
Thomas Weisel Partners
Leerink Swann & Co.
Merrill Lynch International
Wilson HTM
$75
Phenomix Corp. (PHMX) 1/28/08 N/A N/A N/A Morgan Stanley
Credit Suisse (co-lead)
Oppenheimer & Co.
Pacific Growth Equities
$86
Prometheus Laboratories Inc. 12/19/07 N/A N/A N/A Goldman Sachs & Co.
Credit Suisse (co-lead)
$100
RXi Pharmaceuticals Corp. (RXIP; unit of CytRx Corp.) 10/30/07 10.8S N/A N/A N/A N/A
Talecris Biotherapeutics Holdings Corp. (TLCR) 7/30/07 N/A N/A N/A Morgan Stanley
Goldman Sachs & Co.
J.P. Morgan
$1B
Xanodyne Pharmaceuticals Inc. (XANO) 11/9/07 N/A N/A N/A Morgan Stanley
Deutsche Bank (co-lead)
RBC Capital Markets
Natexis Bleichroeder
$86.25
XDx Inc. (XDXI) 10/24/07 N/A N/A N/A J.P. Morgan Securities Inc.
Morgan Stanley & Co. (co-lead)
Piper Jaffray & Co.
JMP Securities LLC
$86.3
FOLLOW-ON OFFERINGS
Biodel Inc. (BIOD)2 1/16/08 3.26S $23.68 23.5 Morgan Stanley & Co. Inc.
JP Morgan Securities Inc.
Leerink Swann LLC
Natixis Bleichroeder Inc.
$77.2
Rigel Pharmaceuticals Inc. (RIGL)3 1/24/08 4S $25.46 35 Credit Suisse Sec. $101.8
WITHDRAWN AND POSTPONED
Merrion Pharmaceuticals Ltd. (MERR)4 4/3/07
1/3/07
4S $6-$7 15 Punk, Ziegel & Co.
Goodbody Stockbrokers
Stanford Group Co.
$26

Notes:
# Unless otherwise indicated, shares are traded on the Nasdaq exchange; general shelf registration statements are not included until action is taken on the filing.
* Stock symbols for companies seeking to complete IPOs are proposed.
@ This column reflects the shares outstanding following the offering, when disclosed.
The value of all offerings is based on either the midpoint of the price range listed in the company's SEC filing or the most recent closing stock price before the offering was announced. In some cases, the company has not disclosed the number of shares to be offered or a price range. Then, the value is the maximum aggregate offering price listed in the SEC filing.
N/A = Not available, applicable or reported.
CDNX = Canadian Venture Exchange; NYSE = New York Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; TSX = Toronto Stock Exchange.
1 Bioheart's overallotment option: 150,000 shares.
2 Biodel's overallotment option: 550,000 shares.
3 Rigel's overallotment option: 600,000 shares.
4 Merrion withdrew its proposed IPO, citing unfavorable market conditions.