Company*
(Country; Symbol)
Company*
(Country;
Symbol)
Type/Product Area Terms/Details (Date)

II. MODIFIED AGREEMENTS

Altair Nano
technologies
Inc.
(ALTI)

Spectrum Pharmaceuticals Inc. (SPPI)

They resolved arbitration proceedings involving RenaZorb, and will continue to advance the product

Altair will get 100,000 Spectrum shares for a milestone payment and 40,000 shares for product development improvements; the product targets kidney disorders (6/7)

Asinex Ltd.*
(Russia)

Ingenium Pharmaceuticals AG* (Germany)

They agreed to continue their collaboration through 2006

The move followed successful lead optimization work done by Asinex; terms were not disclosed (6/6)

Gen-Probe
Inc.
(GPRO)

DiagnoCure Inc. (Canada; TSE:CUR)

The amended and expanded deal focused on the PCA3 prostate cancer marker; also, DiagnoCure will fund research at Gen-Probe

DiagnoCure got exclusive rights to develop in vivo products using the gene, and co-exclusive rights to develop fluorescence in situ hybridization products; Gen-Probe would get royalties on any resulting sales (5/30)

XTL Bio-
pharmaceuticals
Ltd.
(XTLB)

Cubist Pharmaceuticals Inc. (CBST)

Cubist decided to discontinue its funding of HepeX-B, a drug candidate for preventing re-infection with hepatitis B following liver transplantation

Cubist said the required pathway did not make financial sense; Cubist wants to find another partner or negotiate for XTL to regain rights (7/19)

II. TERMINATED AGREEMENTS

EndoBiologics
International
Corp.*

VaxGen Inc. (PK:VXGN)

VaxGen ended a deal for the development of a meningitis B vaccine candidate

VaxGen had funded research and proof-of- concept studies under the May 2005 option agreement (5/30)


Notes:

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

PK = Pink Sheets; TSE = Toronto Stock Exchange.