I. MODIFIED AGREEMENTS

Company* (Country; Symbol)

Company* (Country; Symbol)

Change from
original agreement

Terms/Details (Date)


Discovery
Partners International
Inc.
(DPII)

Theracos Inc.*

Extended medicinal
chemistry program

Financial terms of the milestone-based collaboration were not disclosed (10/22)

Epimmune
Inc.
(EPMN)

Genencor International
Inc.
(GCOR)

Extended collaboration focused on the development of vaccines to treat or prevent hepatitis C, hepatitis B and human papillomaviruses

The agreement began in July 2001 and is extended through September 2004; Genencor fully funds Epimmune's R&D expenses and will pay Epimmune royalties on sales of any products that result; Genencor also would make milestone payments to Epimmune (10/21)

Gene Logic
Inc.
(GLGC)

IDEC Pharmaceuticals Corp. (IDPH)

Extended subscription agreement for the GeneExpress Oncology DataSuite for use in IDEC's drug discovery and development efforts focused on cancer therapies

IDEC's researchers will continue to use the suite's genomic and clinical information on normal and diseased human tissues to support their internal genomics-driven target identification and validation initiatives (10/7)

XOMA Ltd.
(XOMA)

Diagnostic Products Corp. (NYSE:DP)

Expanded agreement to give Diagnostic Products exclusive, worldwide rights to use XOMA technology to develop non-automated, point-of-care, single-sample products

Additional financial and other terms were not disclosed (10/8)

II. TERMINATED AGREEMENTS

Company* (Country; Symbol)

Company* (Country; Symbol)

Change from
original agreement

Terms/Details (Date)


Seattle
Genetics
Inc.
(SGEN)

Genentech Inc.
(NYSE:DNA)

Terminated agreement for the development of SGN-14

Seattle Genetics regains all rights to the anti-CD40 monoclonal antibody, and will continue development in hematological malignancies (10/8)


Notes:

# The information in the chart does not cover agricultural agreements.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

NYSE = New York Stock Exchange