Company*
(Country;
Symbol)

Company*
(Country;
Symbol)

Product

Terms/Details (Date)


Celltech Group
plc
(UK;
LSE:CCH)

Biochemie
GmbH
(Austria;
unit of Novartis AG)

PEGylated antibody fragment-based drugs

Biochemie will manufacture and supply the drugs to Celltech with a fixed annual manufacturing capacity from 2004 to 2010 (9/12)

GeneMachines
Inc.*

Carsen Group
Inc.*
(Canada)

OmniGrid and OmniGrid Accent microarrayers

Exclusive distribution agreement; financial terms were not disclosed (8/29)

Insmed
Inc.
(INSM)

Avecia Biotechnology Inc.* (UK)

SomatoKine, and its component proteins, insulin-like growth factor-1 and insulin-like growth factor binding protein-3

Avecia will manufacture the drug candidate and its component proteins (7/29)

InterMune Inc.
(ITMN)

Accredo Health Inc. (ACDO)

Actimmune

Accredo will distribute Actimmune; financial terms were not disclosed (8/26)

Keryx
Biopharma-
ceuticals Inc.
(KERX)

PolyPeptide
Laboratories
Group* (Denmark)

KRX-123

Agreement for the scaled-up production of KRX-123, a peptide drug candidate for the treatment of hormone-refractory prostate cancer (8/22)

Meditech
Research Ltd.
(Australia; ASX:MTR)

SkyePharma
plc
(UK; LSE:SKP)

Solarase

Reciprocal licensing agreement in which SkyePharma reacquires the territorial rights in certain Pacific Rim territories in return for an up-front payment, a milestone on eventual product registration in Australia or New Zealand, and a royalty on sales; SkyePharma gains the exclusive right to manufacture and market or sublicense Solarase in Australia, New Zealand, Singapore and Malaysia, while Meditech obtains equivalent rights in China, Taiwan, Indonesia and the Philip- pines (9/9)

Ribozyme Pharmaceuticals Inc. (RZYM)

Prime
Synthesis

Inc.*

Ribozyme's new generation of controlled pore glass solid support technology

Prime Synthesis will market Ribozyme's technology exclusively (8/22)


Notes:

# The information in the chart does not cover agricultural agreements.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

ASX = Australian Stock Exchange; LSE = London Stock Exchange; SWX = Swiss Stock Exchange