Biotech Co.* (Country; Symbol)

Biotech Co.* (Country; Symbol)

Product

Terms/Details (Date)


Affymetrix Inc.
(AFFX)

Qiagen NV*
(the Netherlands)

Optimized nucleic acid purification technologies

Qiagen will manufacture products customized for use with GeneChip expression analysis; resulting products will be distributed by Affymetrix for use on the GeneChip systems (6/11)

Agilent Technologies
Inc.
(NYSE:A)

Incyte Genomics Inc. (INCY)

Microarray gene expression products

Agilent will supply Incyte with catalogue and custom microarrays, microarray readers, Rosetta Resolver bioinformatics software and Agilent 1100 liquid chromatographs/mass spectrometry systems (7/10)

Atrix
Laboratories

Inc.
(ATRX)

Biosintetica*
(Brazil) and Tecnofarma* (Argentina)

Eligard, leuprolide acetate for injectable suspension, prostate cancer products

Biosintetica will market the Eligard pro- ducts in Brazil with Tecnofarma having marketing rights in the rest of Latin America, including Mexico; Atrix will manufacture the products; Biosintetica and Tecnofarma will be responsible for regulatory submissions (7/15)

Exact Sciences Corp. (EXAS)

Laboratory
Corp.
of America Holdings (NYSE:
LH)

PreGen-Plus, a screening test for colorectal cancer based on applied genomics

Five-year commercialization partnership; Exact Sciences was paid an initial $15M and an additional $15M would be paid once the product goes to market; additional payments are related to various milestones; the deal is valued at up to $75M (6/27)

GenVec Inc.
(GNVC)

BioReliance
Corp.
(BREL)

BioBypass and TNFerade

Agreement to provide 100-liter scale manufacturing services and related testing for GenVec; the multiyear contract provides for technology transfer, equipment and methods validation and manufacturing activities (7/8)

Genzyme Molecular Oncology
(GZMO)

Silico Insights
Inc.*

SAGE gene expression
technology and i-Sight Discovery pathway informatics platform

The companies will co-market the products (6/24)

Geron Corp.
(GERN) Inc.
(RZYM)

Ribozyme Pharmaceuticals

GRN163, an anticancer drug that inhibits the telomerase enzyme

Ribozyme will manufacture GRN163; financial terms were not disclosed (7/24)

Geron Corp.
(GERN)

Transgenomic
Inc.
(TBIO)

Modified nucleic acid building block compounds

Transgenomic will supply the compounds that Geron will use to synthesize GRN163, Geron's cancer drug, for use in preclinical and clinical studies in 2002 and 2003; financial terms were not disclosed (7/18)

Immuno-
Designed
Molecules SA* (France)

Novavax Inc.
(NVAX)

Prostate-specific antigen

Novavax will manufacture PSA for use in IDM's development programs for prostate cancer vaccines (6/10)

InforMax Inc.
(INMX)

United Bioinformatica
Inc.*
(Canada)

InforMax's desktop analysis tools

Distribution agreement in which United Bioinformatica will provide Canadian researchers access to InforMax's tools for genomics and proteomics research (6/20)

Sonus Pharmaceuticals Inc. (SNUS)

Gensia Sicor Pharmaceuticals Inc. (division of Sicor Inc.; SCRI)

Tocosol Paclitaxel

Companies entered into a manufacturing and supply agreement for Tocosol Paclitaxel, Sonus' drug in Phase II trials (7/1)

Stem Cell Sciences Ltd.* (Australia)

Sosei Co. Ltd.*
(Japan)

Discovery platform technologies

Stem Cell and Sosei formed a Japanese biotech company, Stem Cell Sciences KK, which will exclusively market the discovery platform technologies of SCS and those developed by SCS KK throughout Asia; SCS will market the combined technologies in all other territories and partner with SCS KK to create stem cell-based therapies for the global market (5/31)


Notes:

# The information in the chart does not cover agricultural agreements.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

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