Biotech Co.*
(Country;
Symbol)

Pharma Co. (Country)

Product

Terms/Details (Date)


Celltech Group plc (UK; NYSE:CLL; LSE:CCH)

Lonza Biotec (division of Lonza Group Ltd.; Switzerland)

PEGylated antibody fragment-based drugs

Lonza Biotec will manufacture PEGylated antibody fragment-based drugs for Celltech at its microbial production facility (7/14)

Columbia Laboratories Inc. (AMEX:COB)

Mipharm SpA (Italy)

Striant

Mipharm will market Columbia's Striant (testosterone buccal system) mucoadhesive in Italy; it also will distribute and sell the product; Columbia will receive payments of $1.4M, including the reimbursement of $350,000 in development costs, as well as milestone and royalty payments (6/9)

Corixa Corp. (CRXA)

GlaxoSmithKline plc (UK)

Bexxar

GlaxoSmithKline will be responsible for registration, marketing and sales of Bexxar therapy in Canada; Corixa will manufacture and supply the product to Glaxo, which will pay up-front license fees, milestone payments and royalties on all future Canadian sales (5/29)

Corixa Corp. (CRXA)

MDS Nordion (Canada)

Bexxar

Seven-year manufacturing agreement in which MDS Nordion will continue to radio-label the antibody in Bexxar (6/24)

Crimson Pharmaceutical
Ltd.
(Hong Kong)

Octamer Inc.

Agreement for Crimson to license three drug candidates from Octamer

The compounds are being investigated to treat a variety of diseases including cancer, AIDS and acute inflammatory conditions such as stroke; Crimson obtained exclusive rights to develop and market the licensed compounds in China, Korea, Hong Kong, Taiwan, Singapore and other areas in Southeast Asia (7/21)

CytoGenix Inc. (OTC BB:CYGX)

Phanuel Pursuits Ltd. (British Virgin Islands)

Anti-herpes topical cream

Agreement in which CytoGenix granted Phanuel an option to exclusively license manufacturing and distribution of its anti-herpes topical cream in China (7/17)

ICOS
Corp.
(ICOS)

Eli Lilly and Co.

Two undisclosed clinical candidates being developed by Lilly

The companies entered an agreement in which ICOS will manufacture the candidates (6/6)

GeneMedix plc
(UK; LSE:GMX)

Penang Development Corp. (Malaysia)

Agreement to set up a company in Penang for the development, manufacture and commercialization of human insulin

GeneMedix would outlicense its existing insulin knowledge to a newly formed Malaysian company and help build manufacturing facilities; the investment is anticipated to be $34M in development loans, grants and an issue of equity in the newly formed company to local investors; GeneMedix will receive an up-front payment and potential milestone payments and royalties in return for its outlicensing (6/13)

Pozen Inc.
(POZN)

Nycomed Danmark ApS (Denmark)

MT 100

Agreement for Pozen to license MT 100 to Nycomed for Nordic sales rights; Nycomed will sell the product in Denmark, Sweden, Norway and Finland; Nycomed will pay Pozen a $500,000 up-front fee, as well as milestone payments totaling $1M, and a double-digit royalty on sales (7/1)

SCIL Biomedicals GmbH* (Germany; subsidiary of SCIL Technology Holding GmbH)

Laxdale Ltd. (Scotland) and Scarista Ltd. (UK)

Lyxia

SCIL gained sales and marketing rights in Germany, France, Austria, Benelux, Switzerland, Poland, Hungary, the Czech Republic and Slovakia (6/13)

Synthetic Blood International Inc. (OTC BB:SYBD)

PrimaPharm Inc.

Oxycyte

PrimaPharm will manufacture Oxycyte, a perfluorocarbon blood subsitute, for upcoming clinical trials; it could be useful in treating stroke, heart attack and cancer (7/23)

Viragen Inc. (AMEX:VRA) and Viragen International Inc. (OTC BB:VGNI)

Arriani Pharmaceuticals SA (Greece)

Natural human alpha interferon, Multiferon

Exclusive distribution agreement with Arriani distributing Multiferon in Greece and designated Balkan countries; agreement is worth $9.5M in sales revenues over five years (5/27)

Viragen Inc. (AMEX:VRA) and Viragen International Inc. (OTC BB:VGNI)

CJ Pharma (division of CJ Corp.; South Korea) and subsidiary CJ Hong Kong Ltd.

Natural interferon

CJ Pharma and CJ Hong Kong will exclusively distribute natural interferon in Hong Kong (5/22)


Notes:

# The information in the chart does not cover agricultural agreements or those between biotech companies.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

AMEX = American Stock Exchange; LSE = London Stock Exchange; NYSE = New York Stock Exchange; OTC BB = Over-the-Counter Bulletin Board.