Aastrom Biosciences Inc., of Ann Arbor, Mich., added Alan Wright and Fabrizio Bonanni to its board of directors.

Aquasearch Inc., of Kailua-Kona, Hawaii, formed a medical advisory board and appointed Clifford Dacso its chairman. Separately, Melanie Weaver was named director of clinical operations.

ArQule Inc., of Woburn, Mass., added Ariel Elia to its board of directors.

Cellular Genomics Inc., of New Haven, Conn., appointed Louis Matis president and chief scientific officer.

CollaGenex Pharmaceuticals Inc., of Newtown, Pa., appointed James O'Shea to its board of directors. O'Shea is president and chief operating officer of Sepracor Inc., of Marlborough, Mass.

Connetics Corp., of Palo Alto, Calif., named Sue Preston senior vice president of quality assurance and regulatory affairs.

CV Therapeutics Inc., of Palo Alto, Calif., appointed Scott Greer and Peter Hutt to its board of directors.

Discovery Laboratories Inc., of Doylestown, Pa., appointed Deni Zodda senior vice president, business development.

Endo Pharmaceuticals Holdings Inc., of Chadds Ford, Pa., named Joseph O'Donnell to its board of directors; Peter Lankau senior vice president, U.S. business; Caroline Berry senior vice president, general counsel and secretary; Bradley Galer vice president, scientific affairs; and James Conover vice president, regulatory affairs.

Genentech Inc., of South San Francisco, named David Nagler vice president, human resources.

GeneTrol Biotherapeutics Inc., of Oakland, Calif., appointed David Chen and Jack Olshansky to its board of directors and Bryan Williams as chairman of its scientific advisory board.

Genetronics Biomedical Ltd., of San Diego, named Terry Gibson its chief operating officer and Tazdin Esmail to its board of directors.

Genteric Inc., of Alameda, Calif., named Roland Scollay its vice president of research and chief scientific officer.

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