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Home » RNA sensor technology enables cell-specific targeting
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Drug Design, Drug Delivery & Technologies

RNA sensor technology enables cell-specific targeting

Oct. 11, 2022
By W. Todd Penberthy
Two research teams independently reported in the Oct. 5, 2022, issues of Nature (Duke University) and Nature Biotechnology (Stanford University) on the development of RNA sensing technologies designed to target cell-specific RNA sequences to form a double-stranded RNA:RNA hybrid that is then edited by endogenous ADAR proteins to remove a stop codon and ultimately enabled to express any protein placed within the construct. The target design typically starts from single-cell RNA transcriptomics data that previously identified cell-specific RNA transcriptomics.
BioWorld Science Drug design, drug delivery and technologies

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