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Home » ‘Not a slowdown, a reversal’: Truebinding tackling Alzheimer’s via galectin-3
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Newco news

‘Not a slowdown, a reversal’: Truebinding tackling Alzheimer’s via galectin-3

March 17, 2023
By Jennifer Boggs
In Alzheimer’s, the amyloid beta hypothesis has proved most persistent in terms of drug development efforts to date, but aggregation of other pathogenic factors – phosphorylated tau (p-tau), APOE4, TREM2 and alpha-synuclein, for example – have also emerged as hallmarks of the disease. It’s that aggregation that seven-year-old Truebinding Inc. aims to target with its lead program, TB-006, a monoclonal antibody against galectin-3.
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