The potent pan-RAF inhibitor PHI-501 shows efficacy in BRAF- and NRAS-mutated metastatic melanoma
April 21, 2023
PHI-501 is a novel pan-RAF inhibitor being developed for acute myeloid leukemia. Big data, an artificial intelligence (AI)-based drug discovery platform and cell-based investigation identified PHI-501 as potentially useful against melanoma, and researchers from Pharos Ibio Co. Ltd. presented preclinical evaluation of the drug for this new indication.