Targeting of the heteromeric GPCR CXCR4:LPA1 complex appears promising in the context of cancer and fibrosis
Oct. 13, 2023
Researchers working at with Seoul National University together with GPCR Therapeutics Inc. have focused on targeting pairs of G protein-coupled receptors (GPCRs) starting with the CXC chemokine receptor 4 (CXCR4), which is well known to serve hematopoietic and early developmental functions, while also being required for cancer metastasis.