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BioWorld - Thursday, April 16, 2026
Home » solid tumors

Articles Tagged with ''solid tumors''

Poseida, Astellas hit the road in $550M convertibleCAR deal

May 1, 2024
By Jennifer Boggs
As Poseida Therapeutics Inc. anticipates reporting further data this year from allogeneic CAR T-cell therapy P-MUC1C-ALLO1, for which Astellas Pharma Inc. has nabbed first negotiation rights, the two companies inked a second deal aimed at combining their respective cell therapy platforms in an early stage collaboration targeting solid tumors.
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Cancer

Potent and highly selective CDK7 inhibitor, KRLS-017, shows antitumor efficacy in multiple xenograft models

April 24, 2024
Researchers from Kirilys Therapeutics Inc. presented findings from the preclinical evaluation of KRLS-017, a novel reversible cyclin-dependent kinase 7 (CDK7) inhibitor being developed for the treatment of advanced solid tumors.
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3D representation of tumor
Cancer

ADRX-0706, a next-generation Nectin-4-targeting ADC with improved therapeutic window

April 23, 2024
Researchers from Adcentrx Therapeutics Inc. recently reported preclinical data for the Nectin-4-targeting antibody-drug conjugate (ADC) ADRX-0706, currently in phase I development for the treatment of solid tumors (NCT06036121).
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Immuno-oncology

Series B financing at Pathios to advance GPR65 inhibitor into clinic for solid cancers

April 19, 2024
Pathios Therapeutics Ltd. has raised $25 million in the first close of a series B financing. Proceeds will support continued development of Pathios’ unique approach to cancer immunotherapy focused on GPR65 inhibition.
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Lymphocyte
Immuno-oncology

GT-216, a genetically modified TIL therapy with enhanced antitumor efficacy and persistence

April 19, 2024
Researchers from Zhuhai Grit Biotechnology Co. Ltd. recently presented preclinical characterization of a new genetically modified tumor-infiltrating lymphocyte (TIL) product, GT-216, being developed for the treatment of solid tumors.
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Cancer

Preclinical characterization of AZD-8421, a potent and selective CDK2 inhibitor

April 18, 2024
Researchers from Astrazeneca plc reported preclinical data for AZD-8421, a selective cyclin-dependent kinase 2 (CDK2) inhibitor, currently being evaluated in early-phase clinical trials as a treatment for solid tumors.
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Ribosome as part of an biological cell constructing mRNA molecules
Immuno-oncology

Curevac and MD Anderson collaborate to develop mRNA-based cancer vaccines

April 17, 2024
Curevac NV and The University of Texas MD Anderson Cancer Center have entered into a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.
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Drug R&D concept image.
Cancer

FGFR4 inhibitor BB-102 shows promise for treating solid tumors

April 15, 2024
Fibroblast growth factor receptor 4 (FGFR4) interacts with its ligand, FGF19, to regulate cell proliferation, differentiation and apoptosis.
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Business, data, dollars illustration

VC firm Medicxi invests $40M in China’s D3 Bio

April 9, 2024
By Nuala Moran
Medicxi has made its first ever investment in China – and its biggest single commitment to date – putting $40 million into D3 Bio Inc. The investment by the London-based venture capital firm will accelerate development of D3’s lead program D3S-001, a second generation KRAS G12C inhibitor, which is in phase II development in advanced solid tumors.
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Business, data, dollars illustration

VC firm Medicxi invests $40M in China’s D3 Bio

April 8, 2024
By Nuala Moran
Medicxi has made its first ever investment in China – and its biggest single commitment to date – putting $40 million into D3 Bio Inc. The investment by the London-based venture capital firm will accelerate development of D3’s lead program D3S-001, a second generation KRAS G12C inhibitor, which is in phase II development in advanced solid tumors.
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