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BioWorld - Sunday, April 5, 2026
Home » mRNA

Articles Tagged with ''mRNA''

Single strand RNA
Newco news

In ongoing mRNA evolution, SML Biopharm sights new cancer vaccines

July 21, 2025
By Marian (YoonJee) Chu
No Comments
SML Biopharm Co. Ltd. is harnessing mRNA technology to develop novel immunotherapy-based cancer vaccines, including two candidates for cervical and head and neck cancers caused by human papillomavirus (HPV) infection.
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Circode executives
Newco news

Circode applies circRNA to heart disease drug R&D, in vivo CAR T

July 15, 2025
By Marian (YoonJee) Chu
No Comments
Shanghai Circode Biomed Co. Ltd. is set to begin clinical trials of HM-2002, a circular RNA (circRNA)-based drug for ischemic heart disease, having gained IND clearance in China Jan. 10 and the U.S. on May 30, Circode CEO Chenxiang Tang recently told BioWorld.
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Circode executives
Newco news

Circode applies circRNA to heart disease drug R&D, in vivo CAR T

July 11, 2025
By Marian (YoonJee) Chu
No Comments
Shanghai Circode Biomed Co. Ltd. is set to begin clinical trials of HM-2002, a circular RNA (circRNA)-based drug for ischemic heart disease, having gained IND clearance in China Jan. 10 and the U.S. on May 30, Circode CEO Chenxiang Tang recently told BioWorld.
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Veritas, Mitsubishi Gas Chemical partner for new ASO candidates

July 8, 2025
By Marian (YoonJee) Chu
No Comments
Veritas In Silico Inc. (VIS) entered a joint research agreement with Mitsubishi Gas Chemical Co. Inc. to use VIS’s mRNA structural motif analyzing platform technology, called Ibvis, to develop antisense oligonucleotide drug candidates.
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Jerome Kim, of IVI, speaking at the Global Vaccine Forum
Global Vaccine Forum 2025

Self-amplifying mRNA technology underscored for next big pandemic

July 1, 2025
By Marian (YoonJee) Chu
No Comments
Experts in mRNA convened at the Global Vaccine Forum (GVF) 2025 to weigh the present and future of vaccine technology, including emerging innovations in self-amplifying mRNA (sa-mRNA) and drug delivery platforms.
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Abbvie adds to in vivo CAR T efforts via $2.1B Capstan buy

June 30, 2025
No Comments
Abbvie Inc. is shelling out up to $2.1 billion to acquire CAR T player Capstan Therapeutics Inc., gaining rights to a phase I-stage program targeting CD19 as well as an in vivo cell engineering platform. The announcement comes on the heels of recently published data detailing Capstan’s delivery approach using targeted lipid nanoparticles (tLNPs) and marks Abbvie’s latest foray into the CAR T space.
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Jerome Kim, of IVI, speaking at the Global Vaccine Forum
Global Vaccine Forum 2025

Self-amplifying mRNA technology underscored for next big pandemic

June 27, 2025
By Marian (YoonJee) Chu
No Comments
Experts in mRNA convened at the Global Vaccine Forum (GVF) 2025 to weigh the present and future of vaccine technology, including emerging innovations in self-amplifying mRNA (sa-mRNA) and drug delivery platforms. “Breakthroughs in mRNA and next-generation vaccine platforms are revolutionizing how we prepare for and respond to global health challenges,” Jerome H. Kim, International Vaccine Institute (IVI) director general, told the audience in Seoul, South Korea, June 19.
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Robert Paris, vice president, Moderna
Global Vaccine Forum 2025

Moderna expands mRNA tech to latent viruses, cancer, rare disease

June 24, 2025
By Marian (YoonJee) Chu
No Comments
Post pandemic, Moderna Inc. is broadening the applications of mRNA technology to cancer, rare diseases, latent viruses and respiratory viruses, “taking advantage” of the revenue generated by Spikevax (elasomeran), its mRNA-based vaccine for COVID-19.
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Stock merger illustration

Biontech’s $1.25B Curevac buyout removes mRNA lawsuit uncertainty

June 12, 2025
By Karen Carey
No Comments
Three years after litigation started over technology used in an mRNA vaccine for COVID-19, Biontech SE is acquiring its adversary, Curevac NV, through an all-stock transaction valued at about $1.25 billion. The amount is lower than the $3 billion in backpay Curevac could win through the lawsuit if a low mid-single-digit royalty were awarded, Evercore ISI analysts Jon Miller and Umer Raffat said. But the legal uncertainty has weighed heavily on the company, which shed 30% of its workforce last July and sold off rights to two of its infectious disease vaccines.
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Drug design, drug delivery & technologies

Poly(A) tail mimetics boost gene expression in haploinsufficiency models

April 10, 2025
Writing in Molecular Therapy Nucleic Acids, researchers hypothesized that using poly(A) tail mimetics to enhance mRNA expression from haploinsufficiency-associated genes could be a disease-modifying treatment strategy.
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