An alleged coverup of NIH-funded gain-of-function research at China’s Wuhan Institute of Virology has led to criminal charges against a former career scientist and top aide to Tony Fauci, the head of the National Institute of Allergy and Infectious Diseases in the time of the COVID-19 pandemic.
The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a 5-year $20.8 million grant to a multi-institutional team led by Weill Cornell Medicine investigators for advanced preclinical development of a promising experimental HIV vaccine.
We all look different to HIV, a virus that destroys the immune system. The defensive cells record every interaction with foreign agents, infections from viruses and bacteria, but also with mechanisms occurring within the body, such as microbiome metabolism, the effects of aging, or the development of diseases. At a preconference session at the 13th IAS Conference on HIV Science (IAS 2025), scientists explained the interactions of different microorganisms with HIV.
Writing in Cell Reports, researchers from the National Institute of Allergy and Infectious Diseases (NIAID) and collaborators have presented a multifaceted analysis and structure-function study of a panel of human monoclonal antibodies (hmAbs) targeting AMA1 elicited by natural Plasmodium falciparum infection in a malaria-endemic region in Mali.
Lactiga Inc. has been awarded a multiyear grant by the National Institute of Allergy and Infectious Diseases (NIAID) to accelerate the advancement of the company’s lead asset, LCTG-001.
A recent study published in Nature Communications by researchers at the National Institute of Allergy and Infectious Diseases (NIAID) and collaborators evaluated a replicating RNA (repRNA) vaccine designed to target a contemporary bovine-derived H5N1 virus and compared its efficacy to a vaccine based on a historical H5N1 strain used in stockpiled vaccines.
Malaria remains a significant global health challenge, causing over 600,000 deaths annually despite existing prevention and treatment measures. Current vaccines and monoclonal antibodies (mAbs) against Plasmodium falciparum, such as RTS,S/AS01 and R21, primarily target the central repeat region of the circumsporozoite protein (CSP) but have shown limited efficacy in completely preventing infection.
Neuraminidase (NA) is an essential surface protein of influenza viruses with potential as an effective drug and vaccine target. However, knowledge of the NA antigenic landscape remains limited, and most current influenza vaccines induce antibodies against the surface glycoprotein hemagglutinin.
Researchers from National Institute of Allergy and Infectious Diseases and affiliated organizations presented data from a study that aimed to assess the protective efficacy of the human fusion peptide (FP) broadly neutralizing antibody (bNAb), VRC34.01, along with two FP vaccine-elicited rhesus macaque mAbs, DFPH-a.15 and DF1W-a.01, to protect naïve rhesus macaques against mucosal challenge with SHIV(BG505).
Ceramedix Holding LLC has been awarded a phase IIB Small Business Innovation Research (SBIR) grant valued at approximately US$3 million by the National Institute of Allergy and Infectious Diseases (NIAID) to support the evaluation of the non-clinical pharmacology of its lead drug candidate. The anti-ceramide antibody is in development through the National Institutes of Health (NIH) as a potential therapeutic to mitigate and/or treat illness due to radiation exposure.
