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BioWorld - Saturday, May 16, 2026
Home » CSF-1R inhibitors

Articles Tagged with ''CSF-1R inhibitors''

Cstone’s ROR1 ADC chases Merck’s, plus China biotech data: ASH 24

Dec. 10, 2024
By Marian (YoonJee) Chu
Four Chinese biopharmaceuticals unveiled early data on respective cancer therapies at the American Society of Hematology (ASH) 2024 meet in San Diego, including Cstone Pharmaceuticals Co. Ltd.’s receptor tyrosine kinase-like orphan receptor 1 (ROR1)-inhibiting antibody-drug conjugate (ADC) in phase I study for lymphomas.
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Neurology/psychiatric

Norwegian University of Science and Technology divulges new CSF-1R inhibitors

May 10, 2024
Norwegian University of Science and Technology (NTNU) has synthesized macrophage colony-stimulating factor 1 receptor (CSF-1R; CD115; c-Fms) inhibitors reported to be useful for the treatment of cancer, amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, macular degeneration, osteoarthritis, osteoporosis, rheumatoid arthritis and Alzheimer’s disease, among others.
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Degradation of motor neurons
Neurology/Psychiatric

Grant supports Myrobalan’s development of CSF-1R inhibitor for ALS

Feb. 8, 2024
Myrobalan Therapeutics Inc. has been awarded a $400,000 grant from the ALS Association to support the advancement of its colony-stimulating factor 1 receptor (CSF-1R) inhibitor for the treatment of amyotrophic lateral sclerosis (ALS).
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Neurology/Psychiatric

Myrobalan to use series A funding for CNS neurorestorative therapies

Jan. 11, 2024
Myrobalan Therapeutics Inc. has completed a $24 million series A funding to support development of neurorestorative therapies for CNS diseases.
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Endocrine/Metabolic

Myrobalan Therapeutics presents new CSF-1R inhibitors

Jan. 10, 2024
Researchers at Myrobalan Therapeutics Inc. and Myrobalan Therapeutics Nanjing Co. Ltd. have divulged macrophage colony-stimulating factor 1 receptor (CSF-1R; CD115; c-Fms) inhibitors reported to be useful for the treatment of cancer, autoimmune diseases, neurodegeneration, obesity, metabolic diseases, and inflammatory disorders.
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Multiple sclerosis
Neurology/Psychiatric

ASH-41020, a dendranib nanomedicine, reduces disease severity in EAE preclinical models

Sep. 5, 2023
Researchers from Ashvattha Therapeutics LLC recently reported on ASH-41020, a new dendranib compound acting as a CSF-1R inhibitor with anti-inflammatory and immunomodulatory effects.
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Cancer

Chinese researchers divulge new CSF-1R inhibitors for cancer

July 27, 2023
Shanghai Haiyan Pharmaceutical Technology Co. Ltd. and Yangtze River Pharmaceutical Group have synthesized macrophage colony-stimulating factor 1 receptor (CSF-1R; CD115; c-Fms) inhibitors reported to be useful for the treatment of cancer.
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3D illustration of a osteoclast
Musculoskeletal

Novel purine-based CSF-1R inhibitors disrupt osteoclast differentiation in vitro

June 21, 2023
Researchers from the Norwegian University of Science and Technology (NTNU) reported the discovery of novel colony-stimulating factor 1 receptor (CSF-1R) inhibitors as potential candidates for the treatment of osteoporosis.
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3D representation of tumor microenvironment
Immuno-oncology

Mithra reports promising antitumor activity with CSF-1R inhibitors in preclinical cancer models

June 15, 2023
Mithra Pharmaceuticals SA has announced promising new data from preclinical studies from a colony-stimulating factor 1 receptor (CSF-1R)...
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Neurology/Psychiatric

Sanofi presents selective CSF-1R inhibitor for the treatment of multiple sclerosis

March 30, 2023
The identification and evaluation of the activity of a novel, selective, brain-penetrant macrophage...
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