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BioWorld - Saturday, February 7, 2026
Home » Topics » Analysis and data insight, BioWorld

Analysis and data insight, BioWorld
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Deal values inch closer to 2020; M&As fall way short

Dec. 10, 2021
By Karen Carey
It was a busy year for biopharma deals, but as 2021 nears its end, activity is lagging 2020. BioWorld recorded 1,844 deals valued at $182 billion in 2021 vs. 2,067 deals valued at $198.2 billion for 2020. That puts 2021 behind last year on the volume of deals by more than 10% and on value by about 8%, but there are still three weeks to go.
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Falling digital graph

The ups and downs of CNS diseases; stocks down by 12.5% for the year

Dec. 9, 2021
By Karen Carey
While financings have reached record levels, the stocks of BioWorld’s Neurological Diseases Index are now underground by 12.5%, a trajectory shadowed by the Nasdaq Biotechnology Index, down by 3.45%. The Dow Jones Industrial Average representing the broader markets, however, is up by nearly 13%.
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Aduhelm product image
A look back as we head into 2022

Top Trends of 2021: Controversy much alive over Biogen’s Aduhelm; picture unclear for other AD prospects

Dec. 9, 2021
By Randy Osborne
In 2021, no drug approval garnered as much attention and debate as Biogen Inc.’s Aduhelm (aducanumab). The FDA’s surprise, accelerated approval of Aduhelm for Alzheimer’s disease flew in the face of the recommendation by an advisory committee, causing a stir that included the resignation of three adcom members, along with publicly made claims that the company’s relationship with regulators had become too cozy.
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A look back as we head into 2022

Top trends of 2021: R&D drives investment, SPACs dominate, but crowding, rising burn rates, new rules, threaten smooth ride

Dec. 6, 2021
By Karen Carey
Financings ramped up dramatically in 2015 with $68 billion collected, but the amount does not touch biopharma investment in the last two years. The industry has raised $113 billion in 2021, down from the $134.5 billion full year 2020 total, but more than every five-year combination total from the years 2000 to 2014. It is an increase of 65% over 2015, 200% over 2016, 118% over 2017, 68% over 2018 and 95% over 2019. Both IPOs ($23.7 billion) and venture capital rounds ($37.8 billion) have hit all-time records this year. But will the onslaught of money continue for the industry?
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Money raised by biopharma: 2021 vs. 2020 vs. 2019

Dec. 3, 2021
Total raised in public, private and other financings of biopharma companies, comparing 2021 vs. 2020 vs. 2019.
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Biopharma money raised: Jan. 1-Dec. 2, 2021

Dec. 3, 2021
Year-to-date money raised in public, private and other financings of biopharma companies.
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Hand holding IPO, financial icons

Biopharma money raised by quarter in 2021 (US$M)

Dec. 3, 2021
Biopharma money raised to-date and by quarter in 2021, including public, private and other financings.
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BioWorld and Nasdaq stock indices

Dec. 3, 2021
These graphs compare the performance of the biotech stocks for all of 2021 using the BioWorld Stock Indicator and the Nasdaq Biotech Index.
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Biggest gainers and losers for the week of Nov. 29-Dec. 3, 2021

Dec. 3, 2021
The top 10 biopharma stock gainers and losers for the week.
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Coronavirus vaccine/therapeutics illustration

Boosters, antivirals and Omicron make their debuts, as COVID-19 ravages on

Dec. 1, 2021
By Karen Carey
Whether it’s the highly mutated Omicron variant emerging in South Africa as biopharma researchers scramble to create custom-made vaccines in record time or the institutional mandates juxtaposed with waning vaccine immunity and the ongoing ups and downs of cases and deaths, the SARS-CoV-2 virus continues to dig its ugly spikes into an uncertain and anxious world.
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