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Home » Topics » Analysis and data insight

Analysis and data insight
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Illustration of green and yellow antibodies, DNA

Bifunction conjunction afoot; multiple players competing

March 27, 2025
By Randy Osborne
Bispecific antibodies have gotten plenty of press in recent years, but less prominent in headlines are bifunctional ones – i.e., those that boast one binding site for an antigen and another site for a non-antibody molecule such as a toxin or drug, taking aim at a single target and bringing a secondary function for extra oomph.
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Green approved stamp
Biopharma regulatory actions and approvals February 2025

Global drug approvals hit 47 in February, surpassing 2024 monthly average

March 25, 2025
By Amanda Lanier
The U.S. FDA approved 16 drugs in February, up from 12 in January but still falling short of the 2024 monthly average of 19 approvals. Just two of those were new molecular entities (NMEs), continuing a slower pace compared to the year’s average of slightly more than four NMEs per month.
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Immune checkpoint inhibitors illustration of PD-1, CTLA-4 and PD-L1.

Checkpoint inhibitor journey traces Chinese firms’ path to global revenue

March 25, 2025
By Sudha Saryu Malhotra, Ruchita Kumar, and Garima Kaul
Chinese pharmaceutical companies are making significant inroads into the global oncology market, particularly with the development and approval of immune checkpoint inhibitors. These treatments, which have shown strong efficacy in various cancer indications, are not only transforming the oncology landscape in China but are also gaining traction in high-value international markets, including the U.S.
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3D illustration of mesenchymal stem cells

Nature Cell wins FDA breakthrough designation of Jointstem

March 25, 2025
By Marian (YoonJee) Chu
Nature Cell Co. Ltd. won U.S. FDA breakthrough therapy designation of its autologous adipose-derived mesenchymal stem cell therapy, Jointstem, March 20, becoming the first Korean company to earn the label in the field of cell therapy.
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Dollar sign in light bulb on yellow background

Report shows increased pharma innovation despite rising R&D costs

March 25, 2025
By Nuala Moran
The obesity market is driving pharma’s return on investment (ROI) upward, with the projected return rising to 5.9% overall in 2024, but only reaching 3.8% if GLP-1 assets are excluded. At the same time, the average cost of developing a drug continues to rise and now stands at $2.23 billion, compared to $2.12 billion in 2023, according to Deloitte’s 15th annual analysis of the ROI from pharmaceutical innovation.
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Med-tech gainers and losers for March 17-21, 2025

March 24, 2025
The top 10 med-tech stock gainers and losers for the week.
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Biggest gainers and losers for March 17-21, 2025

March 24, 2025
The top 10 biopharma stock gainers and losers for the week.
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Biopharma money raised: Jan. 1-March 20, 2025

March 21, 2025
Year-to-date money raised in public, private and other financings of biopharma companies.
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Money raised by biopharma

March 21, 2025
Total raised in public, private and other financings of biopharma companies, comparing 2019-2024.
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Test tubes, dropper and capsules
Index insights

Drug developers show mixed performance in early 2025

March 21, 2025
By Amanda Lanier
After finishing 2024 with a 15.25% decline, the BioWorld Drug Developers Index rebounded 6.93% in January, only to fall back to a modest 1.06% gain by the end of February. The Nasdaq Biotechnology Index and the Dow Jones Industrial Average followed a similar pattern, each rising about 5% by the end of January, before closing February at 3.13% and -2.48%, respectively.
Read More
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