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BioWorld - Tuesday, June 2, 2026
Home » Topics » Conferences

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Liver
Endocrine/Metabolic

Liver-expressed ASK1 as potential therapeutic target for obesity and associated diseases

Sep. 29, 2022
Researchers from the University of Zurich presented data from a study that aimed to investigate the impact of liver-specific apoptosis signal regulating kinase 1 (ASK1) overexpression on the development of high-fat diet (HFD)-induced obesity and impaired glucose metabolism.
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Endocrine/Metabolic

BMF-219 improves glycemic control after short-term dosing in rat model of T2DM

Sep. 29, 2022
Researchers from Biomea Fusion Inc. presented preclinical data for the oral menin inhibitor, BMF-219, being developed for the treatment of diabetes.
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Digestive system
Endocrine/Metabolic

Targeting FXR signaling as novel therapeutic strategy in diabetes

Sep. 29, 2022
Farnesoid X receptor (FXR) is a bile acid-activated receptor and in the gut it is mainly expressed in the ileum, promoting transcription of fibroblast growth factor-19 (FGF-19), a hormone with positive effects on energetic and glucose homeostasis.
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3D illustration of nanobubbles as drug delivery technology.
Drug Design, Drug Delivery & Technologies

Antigen-specific peptide-loaded nanobubbles show utility as approach to type 1 diabetes treatment

Sep. 29, 2022
Type 1 diabetes is characterized by the destruction of insulin-producing β cells in the pancreas that leads to severe hyperglycemia if not treated.
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Concept art for blood sugar.
Endocrine/Metabolic

α-MSH, a newly identified regulator of glycemia in human physiology

Sep. 28, 2022
Researchers from University College Dublin and affiliated organizations presented data from a study that aimed to assess the role of α-melanocyte-stimulatory hormone (α-MSH) in diabetes.
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Lung cancer illustration
Cancer

hSSB1 identified as a marker of lung cancer prognosis, inhibitor shows antitumor effects

Sep. 27, 2022
Researchers from Queensland University of Technology and Princess Alexandra Hospital in Australia have shown nucleic acid binding protein 2 (hSSB1), a DNA repair protein, to have prognostic significance for non-small-cell lung cancer (NSCLC). In an analysis of hSSB1 mRNA levels in NSCLC in online databases, higher levels were associated with poor prognosis.
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Cancer cell and DNA
Cancer

IL-27 gene signature is enriched for IFN‑stimulated genes associated with cancer therapy resistance

Sep. 27, 2022
Scientists at Surface Oncology Inc. described data from a study that aimed to evaluate the role of IL-27, a heterodimeric cytokine that plays a role in controlling the intensity and duration of immune system responses, in cancer therapy resistance.
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Lungs
Respiratory

HM-15211 demonstrates efficacy in BLM-induced mouse model of IPF

Sep. 27, 2022
Researchers from Hanmi Science Co. Ltd. presented preclinical data for the novel long-acting glucagon/GIP/GLP-1 triple agonist HM-15211...
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Plant with biochemistry structure
Cancer

Chlorophyll derivative shows promise as anticancer photosensitizer

Sep. 27, 2022
Donghua University and Rudjer Boskovic Institute (RBI) scientists have described the synthesis of a preclinical photosensitizer for anticancer...
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Neural network
Neurology/Psychiatric

AC-0027838 shows analgesic and anti-inflammatory activity in preclinical model

Sep. 27, 2022
Researchers from Alzecure Pharma AB have presented preclinical data on a novel TrkA negative allosteric modulator (NAM), AC-0027838, for...
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