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BioWorld - Friday, September 22, 2023
Home » Topics » Deals and M&A

Deals and M&A
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Optogenetics illustration

Shape, Otsuka ink $1.5B gene therapy alliance targeting ocular diseases

Sep. 8, 2023
By Jennifer Boggs
No Comments
In its second big pharma deal to date, Shape Therapeutics Inc. drew Otsuka Pharmaceutical Co. Ltd. to the table in a potential $1.5 billion-plus collaboration initially aimed at developing gene therapies for ocular diseases. The multitarget agreement, which includes options for additional targets and tissue types, will combine Shape’s AI-driven adeno-associated virus (AAV) platform and Otsuka’s expertise in ophthalmology to develop intravitreally delivered AAV therapies.
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Scientist, microscope and dropper

In a cancer development deal with Seagen, Nurix could bring in up to $3.4B

Sep. 7, 2023
By Lee Landenberger
No Comments
In a mammoth deal with a potentially huge payoff, Nurix Therapeutics Inc. and Seagen Inc. will collaborate to develop what they call a new class of medicines, Degrader-Antibody Conjugates, to create drugs with new mechanisms of action for treating cancer.
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Psychedelic drug- brain illustration

Otsuka to acquire Mindset for $50M in move to bolster psychiatric pipeline

Sep. 5, 2023
By Tamra Sami
No Comments
Otsuka Pharmaceutical Co. Ltd. announced plans to acquire Mindset Pharma Inc. for C$80 million (US$50.76 million) in an all-cash deal that will see Otsuka strengthen its neurology and psychiatric pipeline. Mindset, of Toronto, is developing next-generation psychedelic therapeutics to treat psychiatric and neurological disorders with high unmet needs.
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Digital handshake

Amgen-Horizon deal is back on as FTC steps back

Sep. 1, 2023
By Lee Landenberger
No Comments
The U.S. FTC’s antitrust challenge to Amgen Inc.’s $27.8 billion acquisition of Horizon Therapeutics plc has been resolved. Amgen agreed to do what it said it would do all along: not bundle pharmacy benefit manager rebates on high volume blockbuster drugs Tepezza and Krystexxa.
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Hands holding gears

Acer stabilizes with Zevra merger and Relief deal

Aug. 31, 2023
By Lee Landenberger
No Comments
Zevra Therapeutics Inc. will acquire Acer Therapeutics Inc. in a $91 million deal that combines two companies with expertise in rare diseases. Acer has struggled since its hot flash drug, ACER-801 (osanetant), failed to hit statistical significance in a phase IIa proof-of-concept study in March 2023. The stumble came amidst the launch of Acer’s Olpruva, a sodium phenylbutyrate for oral suspension therapy approved by the U.S. FDA in late December 2022 for treating urea cycle disorders. The day before the Zevra merger was announced, Acer reacquired the worldwide development, commercialization and economic rights to Olpruva from its development partner, Relief Therapeutics Inc.
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Blood cells and destruction of cancer cell

Verismo, U Penn team up on two CD19 binders for novel CAR T

Aug. 29, 2023
By Marian (YoonJee) Chu
No Comments
Verismo Therapeutics Inc., the U.S. subsidiary of South Korea’s HLB Co. Ltd., inked a license agreement with the University of Pennsylvania for two newly discovered CD19 binders – one of which will be used to develop Synkir-310, its investigative CAR T therapy for blood cancers.
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Vaxxas HD-MAP

SK Bioscience, Vaxxas partner to develop needle-free typhoid vaccine

Aug. 29, 2023
By Tamra Sami
No Comments
SK Bioscience Co. Ltd.  and Vaxxas Pty. Ltd. have entered into a joint development agreement that could revolutionize vaccines by developing a vaccine-delivery device combination product using Vaxxas’ high-density microarray patch (HD-MAP) coupled with SK Bioscience’s typhoid vaccine, Skytyphoid.
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Verastem, Genfleet to develop compounds targeting RAS pathways in deal worth up to $625M

Aug. 29, 2023
By Tamra Sami
No Comments
Verastem Oncology Inc. and Genfleet Therapeutics Ltd. have inked a discovery and development deal to advance three oncology discovery programs targeting RAS pathway-driven cancers.
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Vaxxas HD-MAP

SK Bioscience, Vaxxas partner to develop needle-free typhoid vaccine

Aug. 25, 2023
By Tamra Sami
No Comments
SK Bioscience Co. Ltd.  and Vaxxas Pty. Ltd. have entered into a joint development agreement that could revolutionize vaccines by developing a vaccine-delivery device combination product using Vaxxas’ high-density microarray patch (HD-MAP) coupled with SK Bioscience’s typhoid vaccine, Skytyphoid.
Read More
No deal dice

On the SPAC track: Slowdown continues with Ross/Aprinoia sputter

Aug. 24, 2023
By Lee Landenberger and Karen Carey
No Comments
The first special purpose acquisition company (SPAC) merger announced in 2023 has fallen apart. Aprinoia Therapeutics Inc. and Ross Acquisition Corp. II mutually agreed to call off the merger that had been valued at $280 million. The failed deal is part of a larger trend that has gained momentum in the past year as a struggling economy and tighter U.S. SEC restrictions dampened SPAC deals.
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