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BioWorld - Sunday, March 26, 2023
Home » Topics » License, BioWorld Science

License, BioWorld Science
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Neurology/Psychiatric

Biohaven licenses ex-China rights to Highlightll’s TYK2/JAK1 inhibitor for neurological disorders

March 23, 2023
No Comments
Biohaven Ltd. has acquired global rights, excluding China regions, from Hangzhou Highlightll Pharmaceutical Co. Ltd. for TLL-041, now designated BHV-8000, an oral, brain-penetrant, highly selective, dual TYK2/JAK1 inhibitor, for neurological disorders.
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CAR T cell attacking cancer cells
Immuno-oncology

Coimmune exercises option to license IL-18 armored CAR technology from MSK

March 21, 2023
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Coimmune Inc. has exercised its option to obtain an exclusive license to IL-18 armored chimeric antigen receptor (CAR) technology under a prior agreement with Memorial Sloan Kettering Cancer Center (MSK). The company plans to couple the technology with allogeneic cytokine induced killer (CIK) cells to launch the clinical development of CMN-008 (armored CAR-CIK cells), with CD19 as the initial target in B-cell malignancies.
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Test tubes, dropper and capsules
Musculoskeletal

Gilead exercises option to license oral IRAK-4 degrader under collaboration with Nurix

March 21, 2023
No Comments
Gilead Sciences Inc. has exercised its option to exclusively license Nurix Therapeutics Inc.'s investigational targeted protein degrader molecule NX-0479, now designated GS-6791. This bivalent degrader is the first development candidate resulting from the companies' collaboration to discover, develop and commercialize up to five innovative targeted protein degradation therapies.
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Antibodies attacking cancer cell
Immuno-oncology

Eureka Therapeutics licenses antibody targeting mesothelin from NCI

March 15, 2023
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Eureka Therapeutics Inc. has entered into a license agreement with the National Cancer Institute (NCI) to develop and commercialize a novel antibody targeting mesothelin (MSLN) in combination with Eureka's proprietary Artemis T-cell receptor platform.
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Needle syringe with a vaccine vial.
Immune

Modex Therapeutics enters license and collaboration with Merck & Co. for EBV vaccine candidate MDX-2201

March 9, 2023
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Modex Therapeutics Inc., an Opko Health Inc. company, has entered into an exclusive worldwide license and collaboration agreement with Merck & Co. Inc., for the development of MDX-2201, Modex's preclinical nanoparticle vaccine candidate targeting Epstein-Barr virus (EBV).
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Scientist with vial
Inflammatory

Coya gains rights to develop COYA-301 for autoimmune diseases

Feb. 16, 2023
No Comments
Coya Therapeutics Inc. has announced expansion of its exclusive worldwide rights for the development and commercialization of COYA-301, the company's low-dose IL-2 subcutaneous administration product candidate. COYA-301 is intended to enhance regulatory T-cell (Treg) function in vivo to treat the systemic neuro-inflammation underlying certain autoimmune and neurodegenerative diseases.
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Infection

Calibr licenses CLB-073 for tuberculosis to Bill & Melinda Gates Medical Research Institute

Feb. 16, 2023
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Calibr at Scripps Research and the Bill & Melinda Gates Medical Research Institute (Gates MRI) have entered into a strategic licensing agreement to advance development of a novel investigational compound for treatment of tuberculosis (TB).
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Infection

Thylacine licenses exclusive rights to antiviral peptide platform developed at Columbia University

Feb. 15, 2023
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Thylacine Biotherapeutics Inc. has entered into a license agreement with Columbia University for worldwide exclusive rights to develop and commercialize a novel antiviral peptide platform invented and refined at Columbia.
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Coronavirus and antibodies
Infection

Tonix exercises option to license anti-SARS-CoV-2 monoclonal antibodies from Columbia University

Feb. 14, 2023
No Comments
Tonix Pharmaceuticals Holding Corp. has exercised an option to obtain an exclusive license from Columbia University for the development of a portfolio of fully human (TNX-3600) and murine (TNX-4100) monoclonal antibodies for the treatment or prophylaxis of SARS-CoV-2 infection.
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Antibody-drug conjugate illustration
Immuno-oncology

Legochem to develop first-in-class ADC using antibody licensed from Elthera

Feb. 13, 2023
No Comments
Legochem Biosciences Inc. has entered into a license agreement with Elthera AG to develop and commercialize a novel antibody-drug conjugate (ADC) therapy using a monoclonal antibody developed by Elthera.
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