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BioWorld - Saturday, July 25, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Brainomix 360 Stroke platform

Brainomix raises £14M for AI-powered imaging solution for stroke, lung fibrosis

March 20, 2025
By Shani Alexander
Brainomix Ltd. raised £14 million ($18 million) in a series C financing round to expand its AI-powered imaging solution, Brainomix 360 Stroke, into the U.S. market. Funds will also go towards advancing the Brainomix 360 E-Lung, which can accurately predict the progression of lung fibrosis. “This series C round is a vital fundraise for us,” Michalis Papadakis, CEO and co-founder of Brainomix, told BioWorld. “We are in a growth stage where we want to bring this next generation of stroke AI into the U.S. market.”
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Nandoun Abeysekera, founder and CEO, Avasa
Newco news

New Zealand’s Avasa develops world-first arterial coupler

March 19, 2025
By Tamra Sami
New Zealand med-tech startup Avasa Ltd. has developed an arterial coupler that could save surgeons 30 minutes in the operating room to better connect arteries.
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Cardiovascular

GSDMD inhibitor reduces experimental atherosclerosis

March 19, 2025
Atherosclerosis is a chronic inflammatory condition and a known risk for the development of cardiovascular diseases. In animal models of atherosclerosis, macrophage pyroptosis is linked to the development and instability of atherosclerotic plaques, where gasdermin-D (GSDMD) plays a crucial role.
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AltiX AI.i_ComboLab

GE Healthcare Altix AI.i upgrades EP and cath lab capabilities

March 17, 2025
By Annette Boyle
With its Altix AI.i launch, GE Healthcare Technologies Inc. aims to upgrade the user experience and efficiency of its catheterization lab and electrophysiology procedures. The new capabilities apply to the Cardiolab, Mac-Lab and Combolab products. The Alitx Ai.i software upgrades received U.S. FDA clearance in December. CE mark is pending.
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Cross section illustration of ion channel in cell membrane
Drug design, drug delivery & technologies

Series A financing at Maxion Therapeutics to advance Knotbodies for ion channel and GPCR-driven diseases

March 17, 2025
Maxion Therapeutics Ltd. has raised $72 million (£58 million) in a series A financing to support its development of antibody-based Knotbody drugs for ion channel- and G protein-coupled receptor (GPCR)-driven diseases.
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Cardiovascular

Charles University and MFMER divulge new DNA topoisomerase II β inhibitors to treat cardiotoxicity

March 14, 2025
Scientists at Charles University and Mayo Foundation for Medical Education and Research (MFMER) have synthesized DNA topoisomerase II β inhibitors reported to be useful for the treatment of cardiotoxicity.
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3D illustration of Bivacor implanted in chest

Australian patient first to leave hospital with Bivacor TAH

March 13, 2025
By Tamra Sami
An Australian man in his 40s with severe heart failure was implanted with a Bivacor Inc. total artificial heart (TAH) and has been discharged from the hospital. He remained at home with the artificial heart for 100 days until he received a transplant earlier this week.
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Global handshake silhouette

Roche, Zealand $5.3B pact focused on amylin analog for obesity

March 12, 2025
By Nuala Moran
In what it says is the biggest obesity deal to date, Zealand Pharma A/S has signed up Roche AG to a potential $5.3 billion global collaboration and license agreement to develop petrelintide, an amylin analog that is currently in phase IIb development. The two companies will co-develop and co-commercialize petrelintide and combination products, including a fixed-dose combination of petrelintide and CT-388, Roche’s dual GLP-1/GIP receptor agonist.
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Cardiovascular

Lucy Therapeutics discovers new adenosine receptor agonists

March 12, 2025
Lucy Therapeutics Inc. has described adenosine receptor agonists reported to be useful for the treatment of Rett syndrome and chronic heart failure.
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Cardiovascular

FGF21 protects mice from ischemic stroke, study shows

March 12, 2025
Ischemic stroke is a fatal condition caused by an arterial embolism that blocks the blood flow through the cerebral artery, frequently being a cause of mortality and disability. Fibroblast growth factor 21 (FGF21) is likely the only member of the FGF family that may cross the blood-brain barrier. Among its functions, inflammatory regulation, energy metabolism, vascular homeostasis, oxidative stress and tissue repair can be highlighted.
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