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Home » Topics » Disease categories and therapies » Dermatologic

Dermatologic
Dermatologic RSS Feed RSS

Inflammatory

Gilead and Leo Pharma partner on oral STAT6 program

Jan. 13, 2025
Gilead Sciences Inc. and Leo Pharma A/S have established a strategic partnership to accelerate the development and commercialization of Leo’s small-molecule oral STAT6 programs for the treatment of inflammatory diseases.
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Jasper posts positive early data as stock drops

Jan. 8, 2025
By Lee Landenberger
Despite positive preliminary data from its early stage study of treating hives, Jasper Therapeutics Inc. saw its stock drop dramatically on Jan. 8. Results were from the ongoing phase Ib/IIa study of the monoclonal antibody and lead candidate briquilimab in treating chronic spontaneous urticaria, often referred to as hives. The results showed clinical responses across several of the dosing cohorts. The treatment also displayed a favorable safety profile.
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Dermatologic

Nimbus Therapeutics patents new 15-hydroxyprostaglandin dehydrogenase inhibitors

Jan. 8, 2025
Nimbus Therapeutics LLC has disclosed 15-hydroxyprostaglandin dehydrogenase inhibitors reported to be useful for the treatment of alopecia, muscle atrophy and more.
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Stock chart, upward arrow

Hoth’s phase IIa derma data in cancer patients propels its stock

Jan. 7, 2025
By Lee Landenberger
Strong interim safety and efficacy data from Hoth Therapeutics Inc.’s phase IIa study of HT-001 helped boost the company’s stock (NASDAQ:HOTH) on Jan. 7 as shares rose 178% to close at $2.28 each.
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Skin irritation on hands
Inflammatory

Kaken licenses STAT6 program to J&J

Dec. 27, 2024
Kaken Pharmaceutical Co. Ltd. and Johnson & Johnson (J&J) have entered into a license agreement for the global development, manufacturing and commercialization of a STAT6 program for autoimmune and allergic diseases, including atopic dermatitis (AD), developed by Kaken.
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DermR collection device

Skin cancer study: Dermr patch as effective as skin biopsy

Dec. 20, 2024
By Tamra Sami
A new method to diagnose skin cancer was validated for the first time in clinical trials that show Dermr Health Solutions Pty Ltd.’s non-invasive microneedle patch collects near-equivalent genetic information compared to a skin biopsy without pain or cutting.
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Inflammatory

Deepcure discovers oral STAT6 inhibitors for type 2 inflammatory diseases

Dec. 20, 2024
Deepcure Inc. has discovered potent, selective oral small-molecule inhibitors of STAT6. These next-generation STAT6 inhibitors have demonstrated promising oral bioavailability, cell permeability and metabolic stability, and do not target STAT6 for degradation.
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Immune

TAVO-101, a potent anti-TSLP antibody with extended half-life

Dec. 19, 2024
Researchers from Tavotek Biotherapeutics Inc. described the discovery and preclinical characterization of TAVO-101.
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Dermatologic

New TYK2 inhibitors disclosed in Sunshine Lake Pharma patent

Dec. 16, 2024
Sunshine Lake Pharma Co Ltd. has divulged non-receptor tyrosine-protein kinase TYK2 inhibitors reported to be useful for the treatment of multiple sclerosis, psoriasis, rheumatoid arthritis, atopic dermatitis, scleroderma, lupus nephritis, systemic lupus erythematosus and ulcerative colitis, among others.
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Dermatologic

Onquality Pharmaceuticals divulges new JAK inhibitors

Dec. 13, 2024
Onquality Pharmaceuticals China Ltd. has synthesized prodrugs of tofacitinib acting as JAK inhibitors reported to be useful for the treatment of atopic dermatitis, psoriasis and alopecia areata.
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