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BioWorld - Tuesday, January 31, 2023
Home » Topics » Disease categories and therapies » Ear, Nose and Throat

Ear, Nose and Throat
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Ear illustration

Proqr procures strong phase I/II data and an FDA chat for next steps

March 24, 2021
By Lee Landenberger
No Comments
RNA therapy developer Proqr Therapeutics NV’s phase I/II study of adults with Usher syndrome and non-syndromic retinitis pigmentosa met all its key objectives, prompting the company to plan two parallel pivotal phase II/III studies that could start by year-end. The company wasted no time as it has already discussed next steps with the FDA to support the therapy’s registration “as soon as possible,” Aniz Girach, Proqr’s chief medical officer, told investors during a March 24 investor call.
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Ear and sound waves illustration

Frequency hears bad news from a phase IIa study of its lead candidate

March 23, 2021
By Lee Landenberger
No Comments
A phase IIa study of Frequency Therapeutics Inc.’s lead candidate in treating hearing loss showed it fared no better than placebo, but the company said its faith in the candidate is bolstered by the belief the study was hampered by trial design issues and by data from another study.
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Frequency Therapeutics reports phase IIa data on FX-322 in sensorineural hearing loss

March 23, 2021
No Comments

Gene therapy for TMPRSS3 hearing loss shows promise with late intervention in mouse model

March 8, 2021
No Comments

Decibel Therapeutics presents DB-OTO for genetic hearing loss

Feb. 25, 2021
No Comments

Novel model of age-related hearing loss with consistent flat cochlear epithelium phenotype

Feb. 25, 2021
No Comments

Phase III trial of Otividex for Meniere's disease does not meet primary endpoint

Feb. 25, 2021
No Comments

Targeting AMPK-alpha prevents drug-induced hair cell loss and hearing loss

Feb. 22, 2021
No Comments

Preclinical data show SENS-401 reduces loss of residual hearing after cochlear implantation

Jan. 19, 2021
No Comments

Novel AAV gene therapy rescues hearing loss in Syne4-/- mice

Jan. 13, 2021
No Comments
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