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BioWorld - Monday, May 16, 2022
Home » Topics » Immune, BioWorld Asia

Immune, BioWorld Asia
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Peanut allergy
Newco news

Prota Therapeutics achieves clinical remission of peanut allergy in phase IIb trial

March 1, 2022
By Tamra Sami
No Comments
PERTH, Australia – Prota Therapeutics Ltd.’s lead candidate PRT-120 induced clinical remission of peanut allergy in 51% of children in a phase IIb clinical trial. There are currently no curative therapies to treat food allergies, Prota Therapeutics CEO Mimi Tang told BioWorld. Peanut allergy in children can be particularly problematic because the only treatment is avoidance.
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Hands holding arrow-shaped puzzle pieces

Huadong acquires Asia rights to drugs from Kiniksa in $662M deal

March 1, 2022
By Doris Yu
No Comments
Huadong Medicine Co. Ltd.’s wholly owned subsidiary Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. has acquired Asia-Pacific rights to two drugs from Kiniksa Pharmaceuticals Ltd. in a deal worth up to $662 million. “This collaboration aims to bring Kiniksa’s therapeutics to patients in the Asia Pacific Region suffering from severe autoimmune and inflammatory diseases,” said Sanj Patel, chairman and CEO of Kiniksa. “The collaboration also provides nondilutive capital, cost-sharing, and resources for clinical trials to accelerate our drug development and commercialization efforts.”
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Servatus team
Newco news

Servatus advances live microbial biotherapeutics after AU$7.5M capital raise

Jan. 25, 2022
By Tamra Sami
No Comments
PERTH, Australia – After raising AU$7.5 million (US$5.4 million) in a private placement, biopharma company Servatus Ltd. is advancing its microbial biotherapeutics clinical programs targeting serious autoimmune conditions. The Coolum, Queensland-based private company is focused on identifying and developing live microbial biotherapeutics and engineered proteins to treat chronic and autoimmune diseases, as well as non-antibiotic treatments for bacterial infections.
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China flag and vial

Beigene’s siltuximab gets China nod for multicentric Castleman disease as firm preps $3.5B STAR Market listing

Dec. 7, 2021
By Doris Yu
No Comments
Beigene Ltd. has received approval from China’s NMPA to market Sylvant (siltuximab) for the treatment of patients with multicentric Castleman disease, including HIV-negative and human herpes virus-8-negative disease. The green light comes at a good time as the Beijing-headquartered company is preparing for a $3.5 billion listing on Shanghai’s STAR Market, its third listing. The monoclonal antibody siltuximab previously received regulatory approval in the U.S. and Europe.
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Cynata regains rights to Cymerus from Fujifilm after COVID-19 slows development in Japan

Oct. 5, 2021
By Tamra Sami
No Comments
PERTH, Australia – Cynata Therapeutics Ltd. has regained rights to its Cymerus mesenchymal stem cell (MSC) product, CYP-001, for graft-vs.-host disease (GVHD) from former licensee Fujifilm Corp., with the two companies negotiating a new partnership under which Fujifilm will manufacture the product.
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Harbour Biomed prepping for phase III on back of phase II myasthenia gravis data

July 20, 2021
By Elise Mak
No Comments
Harbour Biomed Therapeutics Ltd. said its anti-FcRn monoclonal antibody, batoclimab, generated top-line phase II data in generalized myasthenia gravis, and the company expects to move into a phase III study by the end of this year, with final data reported in April 2022.
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Biocytogen forms partnership and closes new financing round

July 20, 2021
By Doris Yu
No Comments
Having created a profitable preclinical services business, Biocytogen Pharmaceuticals Co. Ltd. is now working to develop its own pipeline of antibody therapeutics, recently inking a partnership with China Resources Biopharmaceutical Co. Ltd. to develop drugs for oncology and immunology indications and raising “tens of millions of dollars” in a new financing round to support the development of its antibody drugs.
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HKEX building

Keymed raises $378M in Hong Kong debut

July 13, 2021
By Gina Lee
No Comments
Keymed Biosciences Inc. debuted on the Hong Kong Stock Exchange (HKSE) on July 8, raising HK$2.94 billion (US$378.48 million) in the process. The company will use the funds raised for the R&D and commercialization of key pipeline candidates.
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Handshake with DNA, molecules
High gear

Fibrogen licensing multiple preclinical assets from Hifibio for $1.1B+

June 22, 2021
By Michael Fitzhugh
No Comments
Just days after Hifibio Therapeutics Inc. closed a $75 million series D financing, Fibrogen Inc. has agreed to pay the antibody specialist $25 million up front and as much as $1.1 billion in milestones for rights to multiple preclinical programs for autoimmune diseases and cancer. The deal includes exclusive rights to Galectin-9 programs, in which the lead asset is expected to enter clinical development in the first quarter of 2023, and options to license all assets in Hifibio's CXCR5 and CCR8 programs.
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Inmagene raises $100M series C to initiate U.S.-China phase II trials of IL-17 inhibitor

June 22, 2021
By Elise Mak
No Comments
Inmagene Biopharmaceuticals Co. Ltd. has raised $100 million in a series C financing to move its IL-17 inhibitor to phase II trials in the U.S. and China.
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