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Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
Inflammatory RSS Feed RSS

Unity shares untied as osteoarthritis of the knee drug fails phase II test

Aug. 17, 2020
By Michael Fitzhugh
Shares of Unity Biotechnology Inc. (NASDAQ:UBX) fell 66.6% to $4.15 on Aug. 17 after UBX-0101, its one-time lead candidate, failed to best a placebo on an established measure of osteoarthritis pain in a phase II study.
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Daiichi Sankyo describes new SIRT6 activators

Aug. 13, 2020

New NLRP3 inflammasome inhibitors discovered at NodThera

Aug. 12, 2020

Daiichi Sankyo patents new SIRT6 activators

Aug. 7, 2020

Honest placebos change brain potentials

Aug. 4, 2020

Kyorin Pharmaceutical discloses new 15-hydroxyprostaglandin dehydrogenase inhibitors

July 30, 2020

Suzhou Zelgen Biosciences identifies new MAP3K5 inhibitors

July 29, 2020

Huihan Medical Technologies discloses new Wnt signaling inhibitors

July 14, 2020

Sanofi expands protein degrader ambitions with $2.15B Kymera deal

July 13, 2020
By Michael Fitzhugh

The industry's expanding quest for protein degraders grew a little larger on July 9 with Sanofi SA tapping Kymera Therapeutics Inc. to advance two new protein degrader programs, one of which will target IRAK4 in patients with immune-inflammatory diseases and another for an undisclosed target. Each program could yield multiple therapies.


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Patric Stenberg and Roger Franklin

Gesynta raises $21M to test novel mechanism in systemic sclerosis

July 8, 2020
By Cormac Sheridan
DUBLIN – Gesynta Pharma AB raised SEK190 million (US$20.6 million) in new funding to move GS-248, a selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), into a phase IIa trial in systemic sclerosis. The study is due to get underway toward the year end. “It’s going to be in the second half of the fourth quarter,” said Patric Stenberg, CEO of Lund, Sweden-based Gesynta.
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