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Musculoskeletal
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Preparation and use of TNF-alpha and MMP inhibitors described by Novartis

Nov. 3, 1998

Safety and efficacy of COX-2 inhibitor established in phase II trials

Nov. 2, 1998

Prosorba Column recommended for approval by FDA advisory panel

Nov. 2, 1998

Vertex and HMR initiate phase I clinical trial with HMR-3480/VX-740

Oct. 30, 1998

New COX-2 inhibitor scheduled for FDA advisory committee review in early December

Oct. 30, 1998

Preparation and pharmaceutical formulations of nimesulide choline salt claimed by Dompe

Oct. 27, 1998

Anika receives nonapprovable letter from FDA for Orthovisc

Oct. 22, 1998

Synvisc approved for treatment of osteoarthritis in Argentina and Brazil

Oct. 20, 1998

Meloxicam comes out ahead of NSAIDs in comparative studies evaluating tolerability

Oct. 9, 1998

Leflunomide market introduction announced

Oct. 7, 1998

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