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BioWorld - Thursday, February 19, 2026
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
Neurology/psychiatric RSS Feed RSS

Neurology/Psychiatric

Open Source Therapeutics identifies new EPHX2 inhibitors

Feb. 23, 2024
Open Source Therapeutics has patented new aromatic substituent-containing (hetero) aryl-imidazole compounds acting as bifunctional epoxide hydrolase 2 (EPHX2; sEH) inhibitors.
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Neurology/Psychiatric

Biogen develops new Huntingtin splicing modulators

Feb. 23, 2024
Huntingtin (HTT; HD; mutant) splicing modulators for the treatment of Huntington’s disease have been disclosed in a Biogen Inc. patent.
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SK-CC

Korea approves SK C&C’s AI solution to diagnose brain infarction

Feb. 22, 2024
By Marian (YoonJee) Chu
South Korea’s MFDS gave regulatory clearance to SK Inc. C&C’s artificial intelligence (AI) solution to diagnose cerebral infarction called Medical Insight+ Brain Infarct on Feb. 22, as a class III device.
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3D illustration of the brain highlighting the substantia nigra
Neurology/Psychiatric

Enveric finds brain disorder compounds across 7 molecular classes

Feb. 22, 2024
Enveric Biosciences Inc. has announced the discovery of multiple, promising novel compounds sourced using the company’s Psybrary platform and proprietary computational chemistry and artificial intelligence (AI) drug-discovery system (Psyai).
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Nelonemdaz

Phase III data positive for GNT's neuroprotective stroke drug

Feb. 20, 2024
By Marian (YoonJee) Chu
South Korean biopharmaceutical firm GNT Pharma Co. Ltd. on Feb. 13 reported positive findings from a domestic phase III trial of its neuroprotectant therapy, nelonemdaz (NEU-2000), for patients with acute ischemic stroke.
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Elderly man with clenched hands holding head

Three strikes for Otsuka’s AVP-786 as it fails in AD-related agitation

Feb. 20, 2024
By Tamra Sami
Otsuka Pharmaceutical Co. Ltd.’s AVP-786 missed the primary endpoint for a third time in a phase III trial for agitation associated with dementia due to Alzheimer’s disease (AD). Two previous phase III trials also failed to show statistical significance for AVP-786.
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Cross section of brainstem

AAAS 2024: Chemo brain, other conditions provide lens for long COVID

Feb. 20, 2024
By Nuala Moran
The biological processes giving rise to the central nervous system symptoms of long COVID remain a mystery. But multiple studies suggest they do not appear to be a result of a direct viral infection of brain tissue. The latest such research, which appeared online in Nature Neuroscience on Feb. 16, 2024, demonstrated that local immune response in brain tissues persisted long after SARS-CoV-2 virus had disappeared.
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Silhouette made of crumpled paper illustrating depression
Neurology/Psychiatric

Dual cannabinoid and serotonin receptor agonist shows antidepressant properties

Feb. 20, 2024
Cannabinoid CB2 receptor and serotonin 5-HT1A receptor agonists have emerged as therapeutic options for their antidepressive and anxiolytic properties, apart from being linked to synergistic antinociceptive activity when used in combination in animal tests.
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Illustration of tau accumulating in a neuron cell.
Neurology/Psychiatric

Voyager Therapeutics reports updates from preclinical programs targeting tau for Alzheimer’s disease

Feb. 20, 2024
Voyager Therapeutics Inc. has announced new data from two preclinical programs targeting pathological tau for the treatment of Alzheimer’s disease.
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Transparent skull with colorful brain illustration
Cancer

Hemogenyx shows chimeric bait receptor can be delivered into the brain via programmed microglial cells

Feb. 19, 2024
The company has developed a method of transplantation of human hematopoietic stem cells that allows their engraftment and differentiation into microglial cells.
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