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BioWorld - Monday, May 4, 2026
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
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Conference data for Sept. 19, 2023: IASLC-WCLC

Sep. 19, 2023
New and updated clinical data presented by biopharma firms at the International Association for the Study of Lung Cancer, 2023 World Conference on Lung Cancer, including: Astrazeneca, Daiichi.
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Neurology/Psychiatric

Viva Star Biosciences divulges new NLRP3 inflammasome inhibitors

Sep. 19, 2023
Viva Star Biosciences (Suzhou) Co. Ltd. has synthesized NLRP3 inflammasome inhibitors reported to be useful for the treatment of cryopyrin-associated periodic syndrome, multiple sclerosis, atherosclerosis, type 2 diabetes, osteoarthritis, cancer, Alzheimer’s disease and Parkinson’s disease.
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Concept art for adeno-associated viral-based gene therapy.
Neurology/Psychiatric

Atamyo files CTA in Europe for ATA-200 gene therapy for limb-girdle muscular dystrophy type 2C/R5

Sep. 19, 2023
Atamyo Therapeutics SAS has filed a clinical trial application (CTA) in Europe for ATA-200, its gene therapy targeting γ-sarcoglycan (SGCG)-related limb-girdle muscular dystrophy type 2C/R5 (LGMD-R5).
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Amyloid plaque on nerve cell
Neurology/Psychiatric

Irisin reduces amyloid-β levels in 3D culture models of Alzheimer’s disease

Sep. 19, 2023
Irisin is a myokine derived from fibronectin type III domain containing 5 (FNDC5) released into the circulation during physical exercise. It is known that FNDC5/irisin stimulates brain-derived neurotrophic factor (BDNF) expression in the hippocampus and also that Alzheimer’s disease (AD) models and brains and cerebrospinal fluid of AD patients have low levels of irisin.
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Neurology/Psychiatric

Lapix’s TIM-3/4 receptor agonist cleared to enter clinic for multiple sclerosis

Sep. 19, 2023
Lapix Therapeutics Inc. has received IND clearance from the FDA to initiate a phase I trial of its first-in-class, immune tolerance restoration small molecule, LPX-TI641, for the treatment of multiple sclerosis (MS).
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Neurology/Psychiatric

Canadian researchers discover new BAX and/or BAK inhibitors for neurodegenerative disorders

Sep. 18, 2023
Researchers at Ontario Institute for Cancer Research and Sunnybrook Research Institute have described isoquinoline derivatives acting as apoptosis regulator BAX and/or BAK inhibitors reported to be useful for the treatment of neurodegenerative disorders.
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Neurology/Psychiatric

Insusense describes new sortilin antagonists

Sep. 18, 2023
Insusense ApS has identified sortilin (NT3; Gp95) antagonists reported to be useful for the treatment of neurodegeneration, cancer, pain, diabetes, diabetic retinopathy, glaucoma, hearing loss and cardiovascular disorders, among others.
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Illustration of Alzheimer’s in the brain.
Neurology/Psychiatric

Study identifies cause of death for Alzheimer’s neurons

Sep. 18, 2023
By Anette Breindl
By creating a new mouse model of Alzheimer’s disease that better recapitulated how the disease plays out in humans, investigators at KU Leuven have gained new insights into how amyloid plaques, tau tangles and neuronal death are related at the molecular level.
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insightec-exablate-neuro-12-13.png

Insightec secures additional CE mark for Exablate Neuro to treat essential tremors

Sep. 15, 2023
By Shani Alexander

Insightec Ltd. broadened its CE mark approval for the Exablate Neuro, a focused ultrasound platform which treats essential tremors, to allow patients to have their second side treated. With some 60 million people estimated to be affected by essential tremor globally, Insightec hopes that with both sides treated, patients will have full body relief from tremor and therefore be able to resume everyday activities.


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Neurology/Psychiatric

New GABA-A modulators reported in Shanghai SIMR Biotech

Sep. 15, 2023
Shanghai SIMR Biotech Co. Ltd. has developed imidazopyridazine derivatives acting as GABA-A modulators and reported to be useful for the treatment of pain, Alzheimer’s disease, multi-infarct dementia, epilepsy, pruritus and stroke.
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