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Home » Topics » Disease categories and therapies » Respiratory

Respiratory
Respiratory RSS Feed RSS

ADAM8 drives severity in acute respiratory distress syndrome trough neutrophil migration

Feb. 16, 2022

Dual PI3K-delta/PI3K-gamma inhibitors identified at National Institute of Pharmaceutical R&D Co.

Feb. 15, 2022

eNAMP-neutralizing MAb reduces ARDS severity in rat and porcine models

Feb. 11, 2022

PNV-5032 reduces airflow resistance by 25% in animal test of allergen-induced asthma

Feb. 10, 2022

Chiesi Farmaceutici identifies new TGFBR1 inhibitors for IPF

Feb. 8, 2022
Lung illustration

$101M series B proves Endeavor worthy in IPF, cancer

Feb. 7, 2022
By Randy Osborne
Endeavor Biomedicines Inc.’s $101 million series B round will let the firm forge ahead with ENV-101 (taladegib), a small-molecule inhibitor of the PTCH1 receptor in the Hedgehog signaling pathway, for cancer and idiopathic pulmonary fibrosis (IPF), as well as ENV-201, described as a potentially best-in-class small-molecule inhibitor of ULK1/2 in KRAS-driven cancers.
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Discovery of novel ATX inhibitor with promising antifibrosis efficacy in rodents

Feb. 2, 2022

Ethris to advance mRNA-based therapeutics for respiratory diseases

Feb. 1, 2022

Blueprint’s Ayvakyt among drugs heading for label extensions in Europe

Jan. 31, 2022
By Richard Staines

Blueprint Medicines Corp.’s cancer drug Ayvakyt (avapritinib) looks set to gain an expanded label in Europe, amid a flurry of decisions from the European Medicines Agency’s CHMP scientific committee. Late last week the CHMP gave a positive opinion for Ayvakyt for treatment of adults with advanced systemic mastocytosis, meaning the drug is likely to gain a further European indication in the coming weeks.


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Lungs wireframe illustration

KCL and Pneumowave unite for trial tackling preventable opioid respiratory deaths

Jan. 28, 2022
By Catherine Longworth
A wearable biosensor developed by Scottish startup Pneumowave Ltd. has been tapped for a clinical trial investigating respiratory depression at King’s College London (KCL). Pneumowave’s respiratory monitoring platform will be used to collect breathing data from patients at risk of experiencing slow and shallow breathing as a side effect of opioid medication.
Read More
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